A dopamine receptor D2 genetic polymorphism associated with transition to mental disorders in a cohort of individuals with at-risk mental state for psychosis

• Published in: Revista brasileira de psiquiatria Vol. 45; no. 3; pp. 268 - 273
• Main Authors: Marques, Julia Hatagami, Talib, Leda Leme, Hortêncio, Lucas, Andrade, Julio Cesar, Alves, Tania Maria, Serpa, Mauricio Henriques, Yamamoto, Guilherme Lopes, van de Bilt, Martinus Theodorus, Rössler, Wulf, Gattaz, Wagner Farid, Loch, Alexandre Andrade
• Format: Journal Article
• Language: English
• Published: Brazil Associação Brasileira de Psiquiatria 2023; Associação Brasileira de Psiquiatria (ABP)
• Subjects: attenuated psychosis; Brief Communication; clinical high risk; Dopamine; flip-flop; PSYCHIATRY; schizophrenia; rs6277; DRD2; dopamine; C957T; UHR; attenuated psychosis; Dopamine; schizophrenia; flip-flop; clinical high risk

We aimed to test the association of 45 single nucleotide polymorphisms (SNPs) and transition to psychiatric disorders in a cohort of individuals with at-risk mental state for psychosis (UHR). Through general population screening, 88 non-help-seeking UHR subjects and 130 healthy control individuals w...