Gestational Intermittent Hypoxia Induces Mitochondrial Impairment in the Geniohyoid Muscle of Offspring Rats

• Published in: Curēus (Palo Alto, CA) Vol. 14; no. 5; p. e25088
• Main Authors: Wongkitikamjorn, Wirongrong, Hosomichi, Jun, Wada, Eiji, Maeda, Hideyuki, Satrawaha, Sirichom, Hong, Haixin, Hayashi, Yukiko K, Yoshida, Ken-ichi, Ono, Takashi
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 17.05.2022; Cureus
• Subjects: Antibodies; Diaphragm (Anatomy); Gene expression; Hypoxia; Immunoglobulins; Metabolism; Muscle contraction; Obstetrics/Gynecology; Pathology; Polymerase chain reaction; Pregnancy; Pulmonology; Rodents; Sleep apnea; Software; Teenagers; United States > US; Germany; obstructive sleep apnea; geniohyoid muscle; offspring rat; intermittent hypoxia; pregnancy; masseter muscles

Introduction Gestational intermittent hypoxia (IH), a hallmark of obstructive sleep apnea during gestation, alters respiratory neural control and diaphragm muscle contractile function in the offspring. The geniohyoid (GH) muscle is innervated by the respiratory-related hypoglossal nerve and plays a...