Union is strength: antiviral and anti-inflammatory drugs for COVID-19

• Published in: Drug discovery today Vol. 26; no. 1; pp. 229 - 239
• Main Authors: Naveja, Jose J., Madariaga-Mazón, Abraham, Flores-Murrieta, Francisco, Granados-Montiel, Julio, Maradiaga-Ceceña, Marco, Alaniz, Víctor Duarte, Maldonado-Rodriguez, Maricruz, García-Morales, Jazmín, Senosiain-Peláez, Juan Pablo, Martinez-Mayorga, Karina
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.01.2021
• Subjects: Anti-Inflammatory Agents - administration & dosage; Anti-Inflammatory Agents - pharmacology; Antiviral Agents - administration & dosage; Antiviral Agents - pharmacology; COVID-19 - virology; COVID-19 Drug Treatment; Drug Repositioning; Drug Therapy, Combination; Humans; Randomized Controlled Trials as Topic; Review

[Display omitted] •Treatment for moderately ill COVID-19 patients might arise from drug repurposing•RdRp, spike protein, and Mpro are relevant SARS-CoV-2 molecular targets.•Targeting human furin may contain viral infection and inflammation.•Molecular docking and clinical experience is useful for dru...