Normalizing hepcidin predicts TMPRSS6 mutation status in patients with chronic iron deficiency

Saved in:
Bibliographic Details
Published inBlood Vol. 132; no. 4; pp. 448 - 455
Main Authors Heeney, Matthew M., Guo, Dongjing, De Falco, Luigia, Campagna, Dean R., Olbina, Gordana, Kao, Paige P.-C., Schmitz-Abe, Klaus, Rahimov, Fedik, Gutschow, Patrick, Westerman, Keith, Ostland, Vaughn, Jackson, Tracy, Klaassen, Robert J., Markianos, Kyriacos, Finberg, Karin E., Iolascon, Achille, Westerman, Mark, London, Wendy B., Fleming, Mark D.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 26.07.2018
American Society of Hematology
Subjects
Adult
Anemia, Iron-Deficiency - blood
Anemia, Iron-Deficiency - genetics
Hepcidins - blood
Humans
Iron - blood
Letter to
Membrane Proteins - genetics
Middle Aged
Mutation
Prognosis
Serine Endopeptidases - genetics
Online AccessGet full text

Cover

Author Heeney, Matthew M.
Markianos, Kyriacos
Kao, Paige P.-C.
Guo, Dongjing
Gutschow, Patrick
Westerman, Mark
Fleming, Mark D.
Olbina, Gordana
Jackson, Tracy
Iolascon, Achille
London, Wendy B.
Ostland, Vaughn
Westerman, Keith
Rahimov, Fedik
Finberg, Karin E.
Schmitz-Abe, Klaus
Klaassen, Robert J.
De Falco, Luigia
Campagna, Dean R.
Author_xml – sequence: 1
  givenname: Matthew M.
  orcidid: 0000-0002-1104-6843
  surname: Heeney
  fullname: Heeney, Matthew M.
  organization: Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA
– sequence: 2
  givenname: Dongjing
  surname: Guo
  fullname: Guo, Dongjing
  organization: Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA
– sequence: 3
  givenname: Luigia
  surname: De Falco
  fullname: De Falco, Luigia
  organization: Department of Molecular Medicine and Medical Biotechnologies, Federico II University Medical School, Naples, Italy
– sequence: 4
  givenname: Dean R.
  surname: Campagna
  fullname: Campagna, Dean R.
  organization: Department of Pathology, Boston Children's Hospital, Boston, MA
– sequence: 5
  givenname: Gordana
  surname: Olbina
  fullname: Olbina, Gordana
  organization: Intrinsic LifeSciences, La Jolla, CA
– sequence: 6
  givenname: Paige P.-C.
  surname: Kao
  fullname: Kao, Paige P.-C.
  organization: Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA
– sequence: 7
  givenname: Klaus
  surname: Schmitz-Abe
  fullname: Schmitz-Abe, Klaus
  organization: Division of Newborn Medicine, Boston, MA
– sequence: 8
  givenname: Fedik
  surname: Rahimov
  fullname: Rahimov, Fedik
  organization: Division of Genetics and Genomics, Department of Medicine, Boston Children's Hospital, Boston, MA
– sequence: 9
  givenname: Patrick
  surname: Gutschow
  fullname: Gutschow, Patrick
  organization: Intrinsic LifeSciences, La Jolla, CA
– sequence: 10
  givenname: Keith
  surname: Westerman
  fullname: Westerman, Keith
  organization: Intrinsic LifeSciences, La Jolla, CA
– sequence: 11
  givenname: Vaughn
  surname: Ostland
  fullname: Ostland, Vaughn
  organization: Intrinsic LifeSciences, La Jolla, CA
– sequence: 12
  givenname: Tracy
  surname: Jackson
  fullname: Jackson, Tracy
  organization: Division of Pediatric Hematology-Oncology, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada
– sequence: 13
  givenname: Robert J.
  surname: Klaassen
  fullname: Klaassen, Robert J.
  organization: Division of Pediatric Hematology-Oncology, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada
– sequence: 14
  givenname: Kyriacos
  surname: Markianos
  fullname: Markianos, Kyriacos
  organization: Department of Pathology, Boston Children's Hospital, Boston, MA
– sequence: 15
  givenname: Karin E.
  surname: Finberg
  fullname: Finberg, Karin E.
  organization: Department of Pathology, Yale University, New Haven, CT
– sequence: 16
  givenname: Achille
  surname: Iolascon
  fullname: Iolascon, Achille
  organization: Department of Molecular Medicine and Medical Biotechnologies, Federico II University Medical School, Naples, Italy
– sequence: 17
  givenname: Mark
  surname: Westerman
  fullname: Westerman, Mark
  organization: Intrinsic LifeSciences, La Jolla, CA
– sequence: 18
  givenname: Wendy B.
  surname: London
  fullname: London, Wendy B.
  organization: Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA
– sequence: 19
  givenname: Mark D.
  orcidid: 0000-0003-0948-4024
  surname: Fleming
  fullname: Fleming, Mark D.
  email: mark.fleming@childrens.harvard.edu
  organization: Department of Pathology, Boston Children's Hospital, Boston, MA
BackLink https://www.ncbi.nlm.nih.gov/pubmed/29895660$$D View this record in MEDLINE/PubMed
BookMark eNp9UU1v1DAUtFAR3Rb-AUI5cgl9_oqTCxKq-KjUUkTLFctxnrtGib3YSVH59Xi7bYFLTyP5zZt5njkgeyEGJOQlhTeUtuyoH2McagZU1cBrpTiw9glZUcnaGoDBHlkBQFOLTtF9cpDzDwAqOJPPyD7r2k42DazI988xTWb0v324qta4sX7wodokHLydc3V59uXrxUVTTctsZh9DlQsuudpyygOGwvnl53Vl1ykGbytfoBrQeVuG9uY5eerMmPHFHR6Sbx_eXx5_qk_PP54cvzutrWj4XJueNSiUUUPXUyklQ2c5VawD16M1gzG0E9w4RinjDQJvnQJBVas6h9IZfkje7nQ3Sz_hYMthyYx6k_xk0o2Oxuv_J8Gv9VW81g2oYiiKwOs7gRR_LphnPflscRxNwLhkzUCKTvKSdqGKHdWmmHNC92BDQW-r0bfV6G01GrjeVVPWXv174sPSfRd__4AlqGuPSefbEEsVCe2sh-gfd_gD93GkYQ
CitedBy_id crossref_primary_10_1042_BSR20202584
crossref_primary_10_1093_jalm_jfaa038
crossref_primary_10_1186_s13023_022_02612_2
crossref_primary_10_1038_s41390_022_02195_5
crossref_primary_10_3324_haematol_2020_264556
crossref_primary_10_3390_jcm13113201
crossref_primary_10_3390_ijms23031917
crossref_primary_10_1146_annurev_med_043021_032816
crossref_primary_10_3389_fphys_2019_01294
crossref_primary_10_1016_j_hoc_2019_01_006
crossref_primary_10_1002_pbc_28122
crossref_primary_10_1016_j_medj_2020_10_004
crossref_primary_10_1002_pbc_28038
crossref_primary_10_1161_ATVBAHA_121_316495
Cites_doi 10.1126/science.1157121
10.1002/ajh.24561
10.1038/ng.130
10.1182/blood-2008-02-139915
10.1182/blood-2015-12-639112
ContentType Journal Article
Copyright 2018 American Society of Hematology
2018 by The American Society of Hematology 2018
Copyright_xml – notice: 2018 American Society of Hematology
– notice: 2018 by The American Society of Hematology 2018
DBID 6I.
AAFTH
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7X8
5PM
DOI 10.1182/blood-2017-03-773028
DatabaseName ScienceDirect Open Access Titles
Elsevier:ScienceDirect:Open Access
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Biology
Anatomy & Physiology
EISSN 1528-0020
EndPage 455
ExternalDocumentID 10_1182_blood_2017_03_773028
29895660
S0006497120320462
Genre Letter
Research Support, N.I.H., Extramural
GrantInformation_xml – fundername: ;
GroupedDBID ---
-~X
.55
1CY
23N
2WC
34G
39C
4.4
53G
5GY
5RE
5VS
6I.
6J9
AAEDW
AAFTH
AAXUO
ABOCM
ABVKL
ACGFO
ADBBV
AENEX
AFOSN
AHPSJ
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
BAWUL
BTFSW
CS3
DIK
DU5
E3Z
EBS
EJD
EX3
F5P
FDB
FRP
GS5
GX1
IH2
K-O
KQ8
L7B
LSO
MJL
N9A
OK1
P2P
R.V
RHF
RHI
ROL
SJN
THE
TR2
TWZ
W2D
W8F
WH7
WOQ
WOW
X7M
YHG
YKV
ZA5
0R~
AALRI
ADVLN
AFETI
AITUG
AKRWK
CGR
CUY
CVF
ECM
EIF
H13
NPM
0SF
AAYXX
CITATION
7X8
5PM
ID FETCH-LOGICAL-c463t-ab26e47a7d9b15552efc317290fbecadaa1943af211236e038f70417879fe5fa3
IEDL.DBID ABVKL
ISSN 0006-4971
IngestDate Tue Sep 17 21:28:13 EDT 2024
Fri Oct 25 23:41:01 EDT 2024
Thu Sep 12 20:11:32 EDT 2024
Sat Nov 02 12:22:48 EDT 2024
Fri Feb 23 02:45:34 EST 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 4
Language English
License This article is made available under the Elsevier license.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c463t-ab26e47a7d9b15552efc317290fbecadaa1943af211236e038f70417879fe5fa3
Notes SourceType-Other Sources-1
ObjectType-Article-1
content type line 63
ObjectType-Correspondence-2
ORCID 0000-0003-0948-4024
0000-0002-1104-6843
OpenAccessLink https://www.sciencedirect.com/science/article/pii/S0006497120320462
PMID 29895660
PQID 2054953017
PQPubID 23479
PageCount 8
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_6071554
proquest_miscellaneous_2054953017
crossref_primary_10_1182_blood_2017_03_773028
pubmed_primary_29895660
elsevier_sciencedirect_doi_10_1182_blood_2017_03_773028
PublicationCentury 2000
PublicationDate 2018-07-26
20180726
PublicationDateYYYYMMDD 2018-07-26
PublicationDate_xml – month: 07
  year: 2018
  text: 2018-07-26
  day: 26
PublicationDecade 2010
PublicationPlace United States
PublicationPlace_xml – name: United States
– name: Washington, DC
PublicationTitle Blood
PublicationTitleAlternate Blood
PublicationYear 2018
Publisher Elsevier Inc
American Society of Hematology
Publisher_xml – name: Elsevier Inc
– name: American Society of Hematology
References Finberg, Heeney, Campagna (bib1) 2008; 40
Donker, Schaap, Novotny (bib6) 2016; 91
De Falco, Silvestri, Kannengiesser (bib5) 2014; 35
Ganz, Olbina, Girelli, Nemeth, Westerman (bib3) 2008; 112
Girelli, Nemeth, Swinkels (bib4) 2016; 127
Du, She, Gelbart (bib2) 2008; 320
30237257 - Blood. 2018 Sep 20;132(12):1355. doi: 10.1182/blood-2018-08-867523
Donker (2019111813070955100_B6) 2016; 91
Du (2019111813070955100_B2) 2008; 320
Girelli (2019111813070955100_B4) 2016; 127
De Falco (2019111813070955100_B5) 2014; 35
Ganz (2019111813070955100_B3) 2008; 112
Finberg (2019111813070955100_B1) 2008; 40
References_xml – volume: 35
  start-page: 1321
  year: 2014
  end-page: 1329
  ident: bib5
  article-title: Functional and clinical impact of novel TMPRSS6 variants in iron-refractory iron-deficiency anemia patients and genotype-phenotype studies
  publication-title: Hum Mutat
  contributor:
    fullname: Kannengiesser
– volume: 112
  start-page: 4292
  year: 2008
  end-page: 4297
  ident: bib3
  article-title: Immunoassay for human serum hepcidin
  publication-title: Blood
  contributor:
    fullname: Westerman
– volume: 40
  start-page: 569
  year: 2008
  end-page: 571
  ident: bib1
  article-title: Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
  publication-title: Nat Genet
  contributor:
    fullname: Campagna
– volume: 320
  start-page: 1088
  year: 2008
  end-page: 1092
  ident: bib2
  article-title: The serine protease TMPRSS6 is required to sense iron deficiency
  publication-title: Science
  contributor:
    fullname: Gelbart
– volume: 91
  start-page: E482
  year: 2016
  end-page: E490
  ident: bib6
  article-title: Iron refractory iron deficiency anemia: a heterogeneous disease that is not always iron refractory
  publication-title: Am J Hematol
  contributor:
    fullname: Novotny
– volume: 127
  start-page: 2809
  year: 2016
  end-page: 2813
  ident: bib4
  article-title: Hepcidin in the diagnosis of iron disorders
  publication-title: Blood
  contributor:
    fullname: Swinkels
– volume: 320
  start-page: 1088
  issue: 5879
  year: 2008
  ident: 2019111813070955100_B2
  article-title: The serine protease TMPRSS6 is required to sense iron deficiency
  publication-title: Science
  doi: 10.1126/science.1157121
  contributor:
    fullname: Du
– volume: 91
  start-page: E482
  issue: 12
  year: 2016
  ident: 2019111813070955100_B6
  article-title: Iron refractory iron deficiency anemia: a heterogeneous disease that is not always iron refractory
  publication-title: Am J Hematol
  doi: 10.1002/ajh.24561
  contributor:
    fullname: Donker
– volume: 40
  start-page: 569
  issue: 5
  year: 2008
  ident: 2019111813070955100_B1
  article-title: Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
  publication-title: Nat Genet
  doi: 10.1038/ng.130
  contributor:
    fullname: Finberg
– volume: 112
  start-page: 4292
  issue: 10
  year: 2008
  ident: 2019111813070955100_B3
  article-title: Immunoassay for human serum hepcidin
  publication-title: Blood
  doi: 10.1182/blood-2008-02-139915
  contributor:
    fullname: Ganz
– volume: 35
  start-page: 1321
  issue: 11
  year: 2014
  ident: 2019111813070955100_B5
  article-title: Functional and clinical impact of novel TMPRSS6 variants in iron-refractory iron-deficiency anemia patients and genotype-phenotype studies
  publication-title: Hum Mutat
  contributor:
    fullname: De Falco
– volume: 127
  start-page: 2809
  issue: 23
  year: 2016
  ident: 2019111813070955100_B4
  article-title: Hepcidin in the diagnosis of iron disorders
  publication-title: Blood
  doi: 10.1182/blood-2015-12-639112
  contributor:
    fullname: Girelli
SSID ssj0014325
Score 2.4162824
SourceID pubmedcentral
proquest
crossref
pubmed
elsevier
SourceType Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 448
SubjectTerms Adult
Anemia, Iron-Deficiency - blood
Anemia, Iron-Deficiency - genetics
Hepcidins - blood
Humans
Iron - blood
Letter to
Membrane Proteins - genetics
Middle Aged
Mutation
Prognosis
Serine Endopeptidases - genetics
Title Normalizing hepcidin predicts TMPRSS6 mutation status in patients with chronic iron deficiency
URI https://dx.doi.org/10.1182/blood-2017-03-773028
https://www.ncbi.nlm.nih.gov/pubmed/29895660
https://search.proquest.com/docview/2054953017
https://pubmed.ncbi.nlm.nih.gov/PMC6071554
Volume 132
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3da9swED9Kyz5expbuI_soGoy9mSiSLFuPaVjp1qWMtR19mpAViRpWNzTJw_bX786yw7INBnsz9hkL_eS730n3AfAGjZyQAX_AshrnmTI6ZsYLk0XhdNBlDGWbJDY71ccX6sNlfrkD0z4XhsIqO92fdHqrrbs7o242R4u6phxfNKemGLc9wBXp4T2B7Bf_zr3J4ZeTj5vDBBxOamSAzjO90GXQIbMepehwQaqaS2SaklNb9r9bqD8Z6O-BlL9YpqOH8KCjlGySRv0IdkIzgP1Jg-709Xf2lrVBnu3u-QDuHPZX96Z9q7cB3J11J-z78PWUSOy3-geaNHYVFr5G48YWtySwWrLz2afPZ2eaXa_TET6jhKT1kpFMqtC6ZLS1y3wqussoi47NA9WpoCTPx3Bx9O58epx1PRgyr7RcZa4SOqjCFXODYOa5CNEj5RCGR0TfzZ0bGyVdRD9SSB24LGPB1RjVgIkhj04-gd3mpgnPgHnHS2UcF14qFWU00pRSVqHKPXpRXg0h6-fdLlKpDdu6KKWwLU6WcLJc2oTTEIoeHLu1ZCxag3-8-brH0uJM0xGJa8LNeolyOQXcovQQniZsN2OhWvVIfjl-dwv1jQBV6t5-0tRXbcVuKuKHvO35f4_4BdzHGyVtKgv9EnZXt-vwCtnQqjroVvsB-gPvT34Cl0wIkA
link.rule.ids 230,315,783,787,888,27581,27936,27937,45675
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED9NnWC8IOj4KDAwEuItqms7H37sqk2FtRViHdoTlpPaWiSWVWv7AH89d3FS0TEJibcouSiWf87d7-z7APiARk5Ihz9glg_iSOnER7oQOvLCJi7JvMvqJLHpLBlfqM-X8eUejNpcGAqrbHR_0Om1tm7u9JvZ7C_LknJ80ZzqdFD3AFekh_eRDaRxB_aHx9_OJtvDBBxOaGSAzjO90GTQIbPuh-hwQaqaS2SaklNb9vst1N8M9G4g5R-W6fQJPG4oJRuGUT-FPVd14XBYoTt9_ZN9ZHWQZ7173oUHx-3Vwaht9daFh9PmhP0Qvs-IxP4of6FJY1duWZRo3NjylgTWKzaffvl6fp6w6004wmeUkLRZMZIJFVpXjLZ2WRGK7jLKomMLR3UqKMnzGVycnsxH46jpwRAVKpHryOYicSq16UIjmHEsnC-QcgjNPaJvF9YOtJLWox8pZOK4zHzK1QDVgPYu9lY-h051U7mXwArLM6UtF4VUykuvpc6kzF0eF-hFFaoHUTvvZhlKbZjaRcmEqXEyhJPh0gScepC24JidJWPQGvzjzfctlgZnmo5IbOVuNiuUiyngFqV78CJgux0L1apH8svxuzuobwWoUvfuk6q8qit2UxE_5G2v_nvE7-BgPJ9OzOTT7Ow1PMKHGW0wi-QNdNa3G3eEzGidv21W_m_togqF
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Normalizing+hepcidin+predicts+TMPRSS6+mutation+status+in+patients+with+chronic+iron+deficiency&rft.jtitle=Blood&rft.au=Heeney%2C+Matthew+M&rft.au=Guo%2C+Dongjing&rft.au=De+Falco%2C+Luigia&rft.au=Campagna%2C+Dean+R&rft.date=2018-07-26&rft.eissn=1528-0020&rft.volume=132&rft.issue=4&rft.spage=448&rft.epage=452&rft_id=info:doi/10.1182%2Fblood-2017-03-773028&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0006-4971&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0006-4971&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0006-4971&client=summon