Acrylonitrile butadiene styrene (ABS) and polycarbonate (PC) filaments three-dimensional (3-D) printer emissions-induced cell toxicity

• Published in: Toxicology letters Vol. 317; pp. 1 - 12
• Main Authors: Farcas, Mariana T., Stefaniak, Aleksandr B., Knepp, Alycia K., Bowers, Lauren, Mandler, William K., Kashon, Michael, Jackson, Stephen R., Stueckle, Todd A., Sisler, Jenifer D., Friend, Sherri A., Qi, Chaolong, Hammond, Duane R., Thomas, Treye A., Matheson, Joanna, Castranova, Vincent, Qian, Yong
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.12.2019
• Subjects: Acrylic Resins - toxicity; Apoptosis - drug effects; Butadienes - toxicity; Cells, Cultured; Cytokines - metabolism; Dose-Response Relationship, Drug; Emerging technologies; Epithelial Cells - drug effects; Epithelial Cells - metabolism; Epithelial Cells - ultrastructure; Humans; In vitro toxicity; Inflammation Mediators - metabolism; Inflammatory response; Nanoparticles - toxicity; Necrosis; Oxidative Stress - drug effects; Particle Size; Polycarboxylate Cement - toxicity; Polystyrenes - toxicity; Printer emitted nanoparticles; Printing, Three-Dimensional; Respiratory Mucosa - drug effects; Respiratory Mucosa - metabolism; Respiratory Mucosa - ultrastructure; Risk Assessment; Time Factors; Inflammatory response; In vitro toxicity; Printer emitted nanoparticles; Emerging technologies

[Display omitted] •Fused filament fabrication 3-D printer emissions consist of particles and organic compounds.•PC filament 3-D printer generated more particles than ABS at an equivalent printing time.•Both PC and ABS 3-D printer emissions induced cell toxicity in human small airway epithelial cells...