Antibody blood-brain barrier efflux is modulated by glycan modification
Drug delivery to the brain is a major roadblock to treatment of Alzheimer's disease. Recent results of the PRIME study indicate that increasing brain penetration of antibody drugs improves Alzheimer's treatment outcomes. New approaches are needed to better accomplish this goal. Based on pr...
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Published in | Biochimica et biophysica acta Vol. 1861; no. 9; pp. 2228 - 2239 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier B.V
01.09.2017
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Subjects | |
Online Access | Get full text |
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