Treatment with metformin glycinate reduces SARS-CoV-2 viral load: An in vitro model and randomized, double-blind, Phase IIb clinical trial

• Published in: Biomedicine & pharmacotherapy Vol. 152; p. 113223
• Main Authors: Ventura-López, Claudia, Cervantes-Luevano, Karla, Aguirre-Sánchez, Janet S., Flores-Caballero, Juan C., Alvarez-Delgado, Carolina, Bernaldez-Sarabia, Johanna, Sánchez-Campos, Noemí, Lugo-Sánchez, Laura A., Rodríguez-Vázquez, Ileana C., Sander-Padilla, Jose G., Romero-Antonio, Yulia, Arguedas-Núñez, María M., González-Canudas, Jorge, Licea-Navarro, Alexei F.
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01.08.2022; The Authors. Published by Elsevier Masson SAS
• Subjects: COVID-19 Drug Treatment; COVID-19 treatment; Humans; Metformin - pharmacology; Metformin - therapeutic use; Metformin glycinate; Prospective Studies; RNA, Viral; SARS-CoV-2; SARS-CoV-2 variants; SARS-CoV-2 viral load; Viral Load; SARS-CoV-2 variants; COVID-19 treatment; Metformin glycinate; SARS-CoV-2 viral load

The health crisis caused by the new coronavirus SARS-CoV-2 highlights the need to identify new treatment strategies for this viral infection. During the past year, over 400 coronavirus disease (COVID-19) treatment patents have been registered; nevertheless, the presence of new virus variants has tri...