The prognostic value of the tumour marker Cyfra 21-1 in carcinoma of head and neck and its role in early detection of recurrent disease

• Published in: British journal of cancer Vol. 83; no. 12; pp. 1696 - 1701
• Main Authors: DOWECK, I, BARAK, M, URI, N, GREENBERG, E
• Format: Journal Article
• Language: English
• Published: Basingstoke Nature Publishing Group 01.12.2000
• Subjects: Aged; Antigens, Neoplasm - analysis; Biological and medical sciences; Biomarkers, Tumor - analysis; Cancer research; Cytokeratin; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Head & neck cancer; Head and Neck Neoplasms - metabolism; Head and Neck Neoplasms - mortality; Head and Neck Neoplasms - pathology; Humans; Keratin-19; Keratins; Male; Medical research; Medical sciences; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Otorhinolaryngology (head neck, general aspects and miscellaneous); Otorhinolaryngology. Stomatology; Predictive Value of Tests; Prognosis; Regular; Survival Analysis; Survival Rate; Tumors; Adenocarcinoma; Human; Carcinoma; Prognosis; Peptide fragment; Head and neck; ENT disease; Tumoral marker; Cytokeratin 19; Malignant tumor; Diagnosis; Recurrent

This study examines a new tumour marker, Cyfra 21-1, as a prognostic marker in predicting the survival of H&N cancer patients, and its correlation with clinical outcome during prolonged follow up of these patients. The study included 67 patients with primary detection of carcinoma of H&N. Th...