Clostridium ljungdahlii represents a microbial production platform based on syngas

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 107; no. 29; pp. 13087 - 13092
• Main Authors: Köpke, Michael, Held, Claudia, Hujer, Sandra, Liesegang, Heiko, Wiezer, Arnim, Wollherr, Antje, Ehrenreich, Armin, Liebl, Wolfgang, Gottschalk, Gerhard, Dürre, Peter, Demain, Arnold L.
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 20.07.2010; National Acad Sciences
• Subjects: Acetates; Acetobacterium woodii; Atmosphere; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Biofuels; Biofuels - microbiology; Biological Sciences; Blotting, Northern; butanol; Butanols; Carbon dioxide; carbon monoxide; Chemicals; Clostridium; Clostridium - genetics; Clostridium - growth & development; Clostridium - metabolism; Clostridium ljungdahlii; Cytochrome; Cytochromes; Data processing; Dehydrogenases; DNA, Bacterial - metabolism; Electroporation; Energy; Energy Metabolism - genetics; Enzymes; Ethanol; Ethanol - metabolism; Ferredoxins; Fuel technology; gene expression; Gene Expression Regulation, Bacterial; genes; Genome, Bacterial - genetics; Genomes; Hydrogen; industry; Ions; Metabolic Networks and Pathways - genetics; Metabolism; Molecular Sequence Data; Moorella thermoacetica; Organic compounds; Plasmids; Proteins; Protons; Recombination, Genetic - genetics; Sodium; Substrate Specificity; Sugar; sugars; Synthesis gas; Translocation

Clostridium ljungdahlii is an anaerobic homoacetogen, able to ferment sugars, other organic compounds, or CO₂/H₂ and synthesis gas (CO/H₂). The latter feature makes it an interesting microbe for the biotech industry, as important bulk chemicals and proteins can be produced at the expense of CO₂, thu...