Angiotensin II Type I Receptor Agonistic Autoantibody Induces Podocyte Injury via Activation of the TRPC6- Calcium/Calcineurin Pathway in Pre-Eclampsia - Yu, Ying; Zhang, Lihong; Xu, Guang; Wu, Zhenghong; Li, Qian; Gu, Yong; Niu, Jianying (Kidney & blood pressure research, 2018)
Keywords: Actin; Activation; Adult; Angiotensin; Angiotensin II; Angiotensin II type I receptor agonistic autoantibody /AT1-AA; Apoptosis; Autoantibodies; Autoantibodies - blood; Autoantibodies - pharmacology; Calcineurin; Calcineurin - metabolism; Calcium; Calcium (intracellular); Calcium - metabolism; Calcium ions; Calcium/calcineurin; Cells, Cultured; Change detection; Chromatography; Endothelin 1; Endothelins; Enzyme-linked immunosorbent assay; Female; Hospitals; Humans; Hypertension; Immunofluorescence; Inhibitors; Intracellular; Kidney diseases; Kinases; Metabolic Networks and Pathways - drug effects; Original Paper; Peptides; Phosphorylation; Podocyte; Podocytes - drug effects; Podocytes - metabolism; Podocytes - pathology; Pre-eclampsia; Pre-Eclampsia - blood; Pre-Eclampsia - metabolism; Preeclampsia; Pregnancy; Proteins; Proteinuria; Receptor, Angiotensin, Type 1 - immunology; Receptor, Angiotensin, Type 1 - therapeutic use; siRNA; TRPC6; TRPC6 Cation Channel - metabolism; Vasoconstriction; United States--US; China; Podocyte; Angiotensin II type I receptor agonistic autoantibody /AT1-AA; TRPC6; Pre-eclampsia; Calcium/calcineurin