The Effect of a Novel form of Extended-Release Gabapentin on Pain and Sleep in Fibromyalgia Subjects: An Open-Label Pilot Study

• Published in: Pain practice Vol. 16; no. 6; pp. 720 - 729
• Main Authors: North, James M., Hong, Kyung-soo J., Rauck, Richard L.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.07.2016
• Subjects: Adult; Aged; Aged, 80 and over; Amines - administration & dosage; Amines - therapeutic use; Analgesics - administration & dosage; Analgesics - therapeutic use; chronic pain; Cyclohexanecarboxylic Acids - administration & dosage; Cyclohexanecarboxylic Acids - therapeutic use; Delayed-Action Preparations; depression; Endpoint Determination; extended release gabapentin (GER); Female; fibromyalgia; Fibromyalgia - complications; Fibromyalgia - drug therapy; Fibromyalgia - psychology; Fibromyalgia Impact Questionnaire; gabapentin; gamma-Aminobutyric Acid - administration & dosage; gamma-Aminobutyric Acid - therapeutic use; gastroretentive gabapentin; Humans; Male; Middle Aged; MOS sleep questionnaire; numeric pain rating system; Pain - drug therapy; Pain - etiology; Pain Measurement; Pilot Projects; Prospective Studies; Quality of Life; Sleep Wake Disorders - drug therapy; Sleep Wake Disorders - etiology; Surveys and Questionnaires; chronic pain; extended release gabapentin (GER); gastroretentive gabapentin; Fibromyalgia Impact Questionnaire; fibromyalgia; gabapentin; numeric pain rating system; MOS sleep questionnaire; depression

Introduction We assessed the efficacy and safety of extended‐release gabapentin in a 15‐week, open‐label, single‐arm, single‐center study in patients with fibromyalgia (FM). Methods Subjects with documented diagnosis of FM were allowed to participate in the study. We opened enrollment to those who h...