Platelet function of whole blood after short‐term cold storage: A prospective in vitro observational study

• Published in: Transfusion (Philadelphia, Pa.) Vol. 63; no. 2; pp. 384 - 392
• Main Authors: Kusudo, Eriko, Murata, Yutaka, Matsumoto, Tsuguhiro, Kawamoto, Shuji, Egi, Moritoki
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.02.2023; Wiley Subscription Services, Inc
• Subjects: acute normovolemic hemodilution; Adenosine diphosphate; Adenosine Diphosphate - metabolism; Blood; Blood platelets; Blood Platelets - metabolism; Blood Preservation; Cold storage; cold temperature; Collagen; Glucose; Hemostasis; Hemostatics; Humans; Lactic acid; Observational studies; Parameters; Platelet Aggregation; Platelet factor 4; Platelets; Prospective Studies; P‐selectin; Room temperature; Statistical analysis; Storage conditions; Storage temperature; acute normovolemic hemodilution; cold temperature; platelet factor 4; P-selectin; platelet aggregation

Background There is no standardized storage temperature of whole blood for acute normovolemic hemodilution (ANH). Study Design and Methods We conducted a prospective observational study to examine the difference in platelet function between short‐term whole blood storage at 4 and 22°C. Venous blood...