Sample size and power considerations for cluster randomized trials with count outcomes subject to right truncation

• Published in: Biometrical journal Vol. 63; no. 5; pp. 1052 - 1071
• Main Authors: Li, Fan, Tong, Guangyu
• Format: Journal Article
• Language: English
• Published: Germany Wiley - VCH Verlag GmbH & Co. KGaA 01.06.2021
• Subjects: arm‐specific exchangeable correlation; Cluster Analysis; Clusters; coefficient of variation; Disease control; Epidemiology; generalized estimating equations; group‐randomized trials; Malaria; Poisson distribution; Population studies; Public health; Randomized Controlled Trials as Topic; Research Design; Sample Size; unequal cluster sizes; Vector-borne diseases; group-randomized trials; Poisson distribution; unequal cluster sizes; arm-specific exchangeable correlation; generalized estimating equations; coefficient of variation

Cluster randomized trials (CRTs) are widely used in epidemiological and public health studies assessing population‐level effect of group‐based interventions. One important application of CRTs is the control of vector‐borne disease, such as malaria. However, a particular challenge for designing these...