Bimodal Imaging‐Visible Nanomedicine Integrating CXCR4 and VEGFa Genes Directs Synergistic Reendothelialization of Endothelial Progenitor Cells

• Published in: Advanced science Vol. 7; no. 24; pp. 2001657 - n/a
• Main Authors: Yu, Bingbo, Dong, Bing, He, Jiang, Huang, Hui, Huang, Jinsheng, Wang, Yong, Liang, Jianwen, Zhang, Jianning, Qiu, Yumin, Shen, Jun, Shuai, Xintao, Tao, Jun, Xia, Wenhao
• Format: Journal Article
• Language: English
• Published: Germany John Wiley & Sons, Inc 01.12.2020; John Wiley and Sons Inc
• Subjects: bimodal imaging; cardiovascular disease; Chemokines; Efficiency; endothelial progenitor cells; Endothelium; Flow cytometry; Gene therapy; Magnetic resonance imaging; Microscopy; Morphology; nanomedicine; Nanoparticles; Particle size; Stem cells; vascular endothelial injury repairing; cardiovascular disease; nanomedicine; bimodal imaging; vascular endothelial injury repairing; endothelial progenitor cells

A major challenge to treat vascular endothelial injury is the restoration of endothelium integrity in which endothelial progenitor cells (EPCs) plays a central role. Transplantation of EPCs as a promising therapeutic means is subject to two interrelated processes, homing and differentiation of EPCs...