The expression of GLP‐1 receptor mRNA and protein allows the effect of GLP‐1 on glucose metabolism in the human hypothalamus and brainstem - Alvarez, Elvira; Martínez, M. Dolores; Roncero, Isabel; Chowen, Julie A.; García‐Cuartero, Beatriz; Gispert, Juan D.; Sanz, Carmen; Vázquez, Patricia; Maldonado, Antonio; De Cáceres, Javier; Desco, Manuel; Pozo, Miguel Angel; et al. (Journal of neurochemistry, 2005)
Keywords: Adult; Aged; Aged, 80 and over; Biological and medical sciences; biological effects; Brain Stem - metabolism; Cell receptors; Cell structures and functions; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Female; Fundamental and applied biological sciences. Psychology; gene expression; Glucagon - metabolism; Glucagon - physiology; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose - metabolism; glucose sensing; human brain; Humans; Hypothalamus - metabolism; Male; Medical sciences; Middle Aged; Molecular and cellular biology; Monoamines receptors (catecholamine, serotonine, histamine, acetylcholine); Neurology; Peptide Fragments - metabolism; Peptide Fragments - physiology; Protein Binding - physiology; Protein Precursors - metabolism; Protein Precursors - physiology; Receptors, Glucagon - biosynthesis; Receptors, Glucagon - genetics; RNA, Messenger - biosynthesis; Human; Phosphates; Statistical analysis; Enzyme; Transferases; GLP-1 receptor; Central nervous system; Glucose; Hypothalamus; Gene expression; Metabolism; Statistical study; Protein; biological effects; Encephalon; human brain; Glucokinase; GLUT-1 glucose transporter; glucagon-like peptide-1 receptor; glucose sensing; Positron; Emission tomography