Tong-Xie-Yao-Fang Regulates 5-HT Level in Diarrhea Predominant Irritable Bowel Syndrome Through Gut Microbiota Modulation

• Published in: Frontiers in pharmacology Vol. 9; p. 1110
• Main Authors: Li, Junchen, Cui, Huantian, Cai, Yuzi, Lin, Jin, Song, Xin, Zhou, Zijun, Xiong, Wantao, Zhou, Huifang, Bian, Yuhong, Wang, Li
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 28.09.2018
• Subjects: 5-HT; diarrhea; gut microbiota; irritable bowel syndrome; Pharmacology; Tong-Xie-Yao-Fang; 5-HT; irritable bowel syndrome; Tong-Xie-Yao-Fang; diarrhea; gut microbiota

Tong-Xie-Yao-Fang (TXYF) has been widely used for the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D) in traditional Chinese medicine. However, its mechanism of action in the treatment of IBS-D remains to be fully understood. Recent reports have shown that species in the gut can i...