Ubiquitin-Proteasome-Collagen (CUP) Pathway in Preterm Premature Rupture of Fetal Membranes

• Published in: Frontiers in pharmacology Vol. 8; p. 310
• Main Authors: Zhao, Xinliang, Dong, Xiaoyan, Luo, Xiucui, Pan, Jing, Ju, Weina, Zhang, Meijiao, Wang, Peirong, Zhong, Mei, Yu, Yanhong, Brown, W. Ted, Zhong, Nanbert
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 02.06.2017
• Subjects: CNV; collagen; lncRNA; Pharmacology; SNV; sPTB; ubiquitin enzymes; CUP pathway; lncRNA; ubiquitin enzymes; collagen; UPS; CNV; SNV; sPTB

Spontaneous preterm birth (sPTB) occurs before 37 gestational weeks, with preterm premature rupture of the membranes (PPROM) and spontaneous preterm labor (sPTL) as the predominant adverse outcomes. Previously, we identified altered expression of long non-coding RNAs (lncRNAs) and message RNAs (mRNA...