Improvement of Xylose Fermentation Ability under Heat and Acid Co-Stress in Saccharomyces cerevisiae Using Genome Shuffling Technique

• Published in: Frontiers in bioengineering and biotechnology Vol. 5; p. 81
• Main Authors: Inokuma, Kentaro, Iwamoto, Ryo, Bamba, Takahiro, Hasunuma, Tomohisa, Kondo, Akihiko
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 20.12.2017
• Subjects: acid tolerance; Bioengineering and Biotechnology; ethanol production; genome shuffling; Saccharomyces cerevisiae; thermotolerance; xylose; acid tolerance; genome shuffling; thermotolerance; xylose; ethanol production; transcriptome analysis; Saccharomyces cerevisiae

Xylose-assimilating yeasts with tolerance to both fermentation inhibitors (such as weak organic acids) and high temperature are required for cost-effective simultaneous saccharification and cofermentation (SSCF) of lignocellulosic materials. Here, we demonstrate the construction of a novel xylose-ut...