Autocrine IL-10 Signaling Promotes Dendritic Cell Type-2 Activation and Persistence of Murine Cryptococcal Lung Infection

• Published in: The Journal of immunology (1950) Vol. 201; no. 7; pp. 2004 - 2015
• Main Authors: Teitz-Tennenbaum, Seagal, Viglianti, Steven P, Roussey, Jonathan A, Levitz, Stuart M, Olszewski, Michal A, Osterholzer, John J
• Format: Journal Article
• Language: English
• Published: United States 01.10.2018

The substantial morbidity and mortality caused by invasive fungal pathogens, including , necessitates increased understanding of protective immune responses against these infections. Our previous work using murine models of cryptococcal lung infection demonstrated that dendritic cells (DCs) orchestr...