Potential Value of miR-221/222 as Diagnostic, Prognostic, and Therapeutic Biomarkers for Diseases

• Published in: Frontiers in immunology Vol. 8; p. 56
• Main Authors: Song, Jialin, Ouyang, Yuanming, Che, Junyi, Li, Xiaoming, Zhao, Yi, Yang, Kejia, Zhao, Xiaotian, Chen, Yinghui, Fan, Cunyi, Yuan, Weien
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 16.02.2017
• Subjects: Immunology; microRNAs; therapy; diagnosis; diseases; biomarker; prognosis; miR-221/222

microRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by base pairing with their target messenger RNAs. Dysregulation of miRNAs is involved in the pathological initiation and progression of many human diseases. miR-221 and miR-222 (miR-221/222) are two highly homologous miRNAs,...