Phenotypic Analysis of Human Lymph Nodes in Subjects With New-Onset Type 1 Diabetes and Healthy Individuals by Flow Cytometry

• Published in: Frontiers in immunology Vol. 10; p. 2547
• Main Authors: Yang, Jennie H. M., Khatri, Leena, Mickunas, Marius, Williams, Evangelia, Tatovic, Danijela, Alhadj Ali, Mohammad, Young, Philippa, Moyle, Penelope, Sahni, Vishal, Wang, Ryan, Kaur, Rejbinder, Tannahill, Gillian M., Beaton, Andrew R., Gerlag, Danielle M., Savage, Caroline O. S., Napolitano Rosen, Antonella, Waldron-Lynch, Frank, Dayan, Colin M., Tree, Timothy I. M.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 31.10.2019
• Subjects: autoimmunity; biomarker; immune monitoring; Immunology; lymph node; type 1 diabetes; type 1 diabetes; immune monitoring; autoimmunity; biomarker; lymph node

Ultrasound guided sampling of human lymph node (LN) combined with advanced flow cytometry allows phenotypic analysis of multiple immune cell subsets. These may provide insights into immune processes and responses to immunotherapies not apparent from analysis of the blood. Ultrasound guided inguinal...