Generation of gene corrected human isogenic iPSC lines (IDVi003-A_CR13, IDVi003-A_CR21, IDVi003-A_CR24) from an inherited retinal dystrophy patient-derived IPSC line ITM2B-5286-3 (IDVi003-A) carrying the ITM2B c.782A > C variant using CRISPR/Cas9

• Published in: Stem cell research Vol. 71; p. 103166
• Main Authors: Ben yacoub, Tasnim, Letellier, Camille, Wohlschelegel, Juliette, Condroyer, Christel, Slembrouck-Brec, Amélie, Goureau, Olivier, Zeitz, Christina, Audo, Isabelle
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.09.2023; Elsevier

The ITM2B-related retinal dystrophy (ITM2B-RD) was identified within patients carrying the autosomal dominant variant [c.782A > C, p.(Glu261Ala)] in ITM2B from whom induced pluripotent stem cell (IPSC) lines were previously generated. Here, we report the generation of three isogenic control iPSC...