Clinical implications of pediatric biliary intraepithelial neoplasia diagnosed from a choledochal cyst specimen

• Published in: World journal of surgical oncology Vol. 22; no. 1; p. 105
• Main Authors: Gang, Sujin, Kwon, Hyunhee, Song, In Hye, Namgoong, Jung-Man
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.04.2024; BMC
• Subjects: Bile Duct Neoplasms - diagnosis; Bile Duct Neoplasms - epidemiology; Bile Duct Neoplasms - surgery; Bile Ducts, Intrahepatic - pathology; Bile Pigments; Biliary intraepithelial neoplasia; Carcinogenesis; Carcinoma in Situ - diagnosis; Carcinoma in Situ - surgery; Care and treatment; Child; Child, Preschool; Children; Cholangiocarcinoma; Cholangiocarcinoma - diagnosis; Cholangiocarcinoma - epidemiology; Cholangiocarcinoma - surgery; Choledochal Cyst - diagnosis; Choledochal Cyst - epidemiology; Choledochal Cyst - surgery; Choledochal cysts; Health aspects; Humans; Infant; Inflammation; Pediatric; Retrospective; South Korea; Biliary intraepithelial neoplasia; Choledochal cysts; Pediatric; Cholangiocarcinoma; Retrospective

Biliary intraepithelial neoplasia (BilIN), a noninvasive precursor of cholangiocarcinoma, can manifest malignant transformation. Since cholangiocarcinoma (CCA) may progress due to chronic inflammation in the bile ducts and gallbladder, choledochal cysts are considered a precursor to CCA. However, Bi...