Technoeconomic Modeling of Plant-Based Griffithsin Manufacturing

• Published in: Frontiers in bioengineering and biotechnology Vol. 6; p. 102
• Main Authors: Alam, Aatif, Jiang, Linda, Kittleson, Gregory A., Steadman, Kenneth D., Nandi, Somen, Fuqua, Joshua L., Palmer, Kenneth E., Tusé, Daniel, McDonald, Karen A.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 24.07.2018
• Subjects: antiviral; Bioengineering and Biotechnology; biomanufacturing; cost; economics; Griffithsin; microbicide; biomanufacturing; economics; cost; microbicide; modeling; antiviral; Griffithsin

Griffithsin is a marine algal lectin that exhibits broad-spectrum antiviral activity by binding oligomannose glycans on viral envelope glycoproteins, including those found in HIV-1, HSV-2, SARS, HCV and other enveloped viruses. An efficient, scalable and cost-effective manufacturing process for Grif...