Chaperonin-Containing TCP1 Complex (CCT) Promotes Breast Cancer Growth Through Correlations With Key Cell Cycle Regulators

• Published in: Frontiers in oncology Vol. 11; p. 663877
• Main Authors: Ghozlan, Heba, Showalter, Adrian, Lee, Eunkyung, Zhu, Xiang, Khaled, Annette R.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 30.04.2021
• Subjects: luminal A; node; oncogene; Oncology; proliferation; targeting; tumorigenesis; node; targeting; tumorigenesis; proliferation; oncogene; luminal A

Uncontrolled proliferation as a result of dysregulated cell cycling is one of the hallmarks of cancer. Therapeutically targeting pathways that control the cell cycle would improve patient outcomes. However, the development of drug resistance and a limited number of inhibitors that target multiple ce...