Development of an Oncogenic Driver Alteration Associated Immune-Related Prognostic Model for Stage I-II Lung Adenocarcinoma

• Published in: Frontiers in oncology Vol. 10; p. 593022
• Main Authors: Xu, Jian-Zhao, Gong, Chen, Xie, Zheng-Fu, Zhao, Hua
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 28.01.2021
• Subjects: Gene Expression Omnibus; immune-related prognostic model; lung adenocarcinoma; oncogenic driver alterations; Oncology; The Cancer Genome Atlas; tumor microenvironment; immune-related prognostic model; oncogenic driver alterations; tumor microenvironment; Gene Expression Omnibus; lung adenocarcinoma; The Cancer Genome Atlas

Lung adenocarcinoma (LUAD) needs to be stratified for its heterogeneity. Oncogenic driver alterations such as mutation, translocation, translocation, and mutation predict response to treatment for LUAD. Since oncogenic driver alterations may modulate immune response in tumor microenvironment that ma...