Application of Nonphosphorylative Metabolism as an Alternative for Utilization of Lignocellulosic Biomass

Production of chemicals via fermentation has been evolving over the past 30 years in search of economically viable systems. Thus far, there have been few industrially relevant chemicals that have seen commercialization, examples being lactic acid and ethanol. Currently, many of these fermentation pr...

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Published inFrontiers in microbiology Vol. 8; p. 2310
Main Authors McClintock, Maria K, Wang, Jilong, Zhang, Kechun
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 23.11.2017
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Abstract Production of chemicals via fermentation has been evolving over the past 30 years in search of economically viable systems. Thus far, there have been few industrially relevant chemicals that have seen commercialization, examples being lactic acid and ethanol. Currently, many of these fermentation processes still compete with food sources. In order to reduce this competition fermentation of alternative feedstocks, such as lignocellulosic biomass must to be utilized. Hemicellulosic sugars can be employed effectively for the production of chemicals by incorporating nonphosphorylative metabolism. This review covers nonphosphorylative metabolism, the pathways and enzymes involved, as well as the products that have been produced using nonphosphorylative metabolism.
AbstractList Production of chemicals via fermentation has been evolving over the past 30 years in search of economically viable systems. Thus far, there have been few industrially relevant chemicals that have seen commercialization, examples being lactic acid and ethanol. Currently, many of these fermentation processes still compete with food sources. In order to reduce this competition fermentation of alternative feedstocks, such as lignocellulosic biomass must to be utilized. Hemicellulosic sugars can be employed effectively for the production of chemicals by incorporating nonphosphorylative metabolism. This review covers nonphosphorylative metabolism, the pathways and enzymes involved, as well as the products that have been produced using nonphosphorylative metabolism.
Author Wang, Jilong
McClintock, Maria K
Zhang, Kechun
AuthorAffiliation Department of Chemical Engineering and Materials Science, University of Minnesota , Minneapolis, MN , United States
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  givenname: Jilong
  surname: Wang
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  givenname: Kechun
  surname: Zhang
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  organization: Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN, United States
BackLink https://www.ncbi.nlm.nih.gov/pubmed/29218038$$D View this record in MEDLINE/PubMed
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Keywords Metabolic Engineering
pathway design
biochemicals
nonphosphorylative metabolism
lignocellulose
Language English
License This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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Edited by: Xueyang Feng, Virginia Tech, United States
Reviewed by: Zhiguang Zhu, Tianjin Institute of Industrial Biotechnology (CAS), China; Meng Wang, Tianjin Institute of Industrial Biotechnology (CAS), China
This article was submitted to Microbial Physiology and Metabolism, a section of the journal Frontiers in Microbiology
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Snippet Production of chemicals via fermentation has been evolving over the past 30 years in search of economically viable systems. Thus far, there have been few...
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StartPage 2310
SubjectTerms biochemicals
lignocellulose
Metabolic Engineering
Microbiology
nonphosphorylative metabolism
pathway design
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Title Application of Nonphosphorylative Metabolism as an Alternative for Utilization of Lignocellulosic Biomass
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