Size- and time-dependent alteration in metabolic activities of human hepatic cytochrome P450 isozymes by gold nanoparticles via microsomal coincubations - Ye, Meiling; Tang, Ling; Luo, Mengjun; Zhou, Jing; Guo, Bin; Liu, Yangyuan; Chen, Bo (Nanoscale research letters, 2014)
Keywords: Adenine; Chemistry and Materials Science; CYP2D6 protein; Cytochrome; Cytochrome P450; Cytochromes P450; Drug dosages; Enzymes; Gold; Inactivation; Isoenzymes; Light scattering; Liver; Materials Science; Membrane proteins; Membranes; Metabolism; Microsomes; Molecular Medicine; Nano Express; Nanochemistry; Nanoparticles; Nanoscale Science and Technology; Nanotechnology; Nanotechnology and Microengineering; Nicotinamide; Nicotinamide adenine dinucleotide; Photon correlation spectroscopy; Proteins; Spectroscopy; Tannic acid; Time dependence; Ultraviolet spectroscopy; Zeta potential; Inhibition; Incubation; Nanoprecipitation; Microsome; Cytochrome P450; Gold nanoparticle