Molecular mechanisms of viral hepatitis induced hepatocellular carcinoma

• Published in: World journal of gastroenterology : WJG Vol. 26; no. 38; pp. 5759 - 5783
• Main Authors: D'souza, Simmone, Lau, Keith CK, Coffin, Carla S, Patel, Trushar R
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 14.10.2020
• Subjects: Carcinoma, Hepatocellular; Hepatitis B - complications; Hepatitis B virus - genetics; Hepatitis, Viral, Human; Humans; Liver Neoplasms; Review; Hallmarks of cancer; Viral hepatitis; Hepatitis delta virus co-infection; Molecular mechanisms; Hepatocellular carcinoma; Hepatitis B virus; Hepatitis C virus; Chronic viral infection

Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead to cirrhosis, cancer, and liver failure. Liver cancer is the third leading cause of cancer-associated mortality, of which hepatocellular carcinoma (HCC) represents 90% of all primary liver cancers. Solid...