TNX-1500, a crystallizable fragment–modified anti-CD154 antibody, prolongs nonhuman primate cardiac allograft survival - Miura, Shuhei; Habibabady, Zahra A.; Pollok, Franziska; Ma, Madelyn; Rosales, Ivy A.; Kinoshita, Kohei; Pratts, Shannon; McGrath, Gannon; Chaban, Ryan; Fogarty, Siobhan; Meibohm, Bernd; Daugherty, Bruce; et al. (American journal of transplantation, 2023)
Keywords: alloantibody; Allografts; Animals; anti-CD154 monoclonal antibody; Antibodies, Monoclonal - pharmacology; Antibodies, Monoclonal - therapeutic use; Antibodies, Monoclonal, Humanized; cardiac allograft survival; CD40 Ligand; costimulation pathway; Graft Rejection - etiology; Graft Rejection - prevention & control; Graft Survival; heart transplantation; Isoantibodies; nonhuman primate; Primates; cardiac allograft survival; alloAb; TREG; MHC; nonhuman primate; BL; ISHLT; FcγRIIa; BW; TEFF; NHP; Fc; loTNX; TNX; d; heart transplantation; AMR; MMF; alloantibody; EOS; mAb; MST; ACR; anti-CD154 monoclonal antibody; costimulation pathway; Bx; CVL; CAV; SEM; Ig; sTNX; ELISA