Candida albicans Mycofilms Support Staphylococcus aureus Colonization and Enhances Miconazole Resistance in Dual-Species Interactions

• Published in: Frontiers in microbiology Vol. 8; p. 258
• Main Authors: Kean, Ryan, Rajendran, Ranjith, Haggarty, Jennifer, Townsend, Eleanor M, Short, Bryn, Burgess, Karl E, Lang, Sue, Millington, Owain, Mackay, William G, Williams, Craig, Ramage, Gordon
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 23.02.2017
• Subjects: Microbiology; Candida albicans; extracellular DNA; miconazole; Staphylococcus aureus; biofilm

Polymicrobial inter-kingdom biofilm infections represent a clinical management conundrum. The presence of co-isolation of bacteria and fungi complicates the ability to routinely administer single antimicrobial regimens, and synergy between the microorganisms influences infection severity. We therefo...