Circulating Endothelial Progenitor Cells Present an Inflammatory Phenotype and Function in Patients With Alcoholic Liver Cirrhosis

• Published in: Frontiers in physiology Vol. 9; p. 556
• Main Authors: Kaur, Savneet, Sehgal, Rashi, Shastry, Saggere M, McCaughan, Geoffrey, McGuire, Helen M, Fazekas St de Groth, Barbara, Sarin, Shiv, Trehanpati, Nirupma, Seth, Devanshi
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 22.05.2018
• Subjects: alcoholic liver cirrhosis; angiogenesis; CD45; endothelial progenitor cells; inflammation; mass cytometry CyTOF; Physiology; alcoholic liver cirrhosis; inflammation; angiogenesis; endothelial progenitor cells; CD34; CD45; mass cytometry CyTOF; CD133

Endothelial progenitor cells (EPCs) have been implicated in liver injury and repair. However, the phenotype and potential of these heterogenous EPCs remain elusive. In particular, their involvement in the pathogenesis of alcoholic liver cirrhosis (ALC) remains unclear. The current study extensively...