miRNA dysregulation in cancer: towards a mechanistic understanding

• Published in: Frontiers in genetics Vol. 5; p. 54
• Main Authors: Palanichamy, Jayanth Kumar, Rao, Dinesh S
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 18.03.2014
• Subjects: genetic redundancy; Genetics; microRNA profiling; MicroRNAs; non-genetic heterogeneity; Single-Cell Analysis; microRNAs; microRNA profiling; genetic redundancy; single-cell studies; non-genetic heterogeneity

It is now well known that gene expression is intricately regulated inside each cell especially in mammals. There are multiple layers of gene regulation active inside a cell at a given point of time. Gene expression is regulated post-transcriptionally by microRNAs and other factors. Mechanistically,...