Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes

• Published in: World journal of gastroenterology : WJG Vol. 24; no. 43; pp. 4846 - 4861
• Main Authors: McGuigan, Andrew, Kelly, Paul, Turkington, Richard C, Jones, Claire, Coleman, Helen G, McCain, R Stephen
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 21.11.2018
• Subjects: Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Biomarkers, Tumor - analysis; Carcinoma, Pancreatic Ductal - diagnosis; Carcinoma, Pancreatic Ductal - epidemiology; Carcinoma, Pancreatic Ductal - pathology; Carcinoma, Pancreatic Ductal - therapy; Chemoradiotherapy, Adjuvant - methods; Early Detection of Cancer - methods; Humans; Incidence; Mass Screening - methods; Neoadjuvant Therapy - methods; Pancreas - pathology; Pancreas - surgery; Pancreatectomy - methods; Pancreatic Neoplasms - diagnosis; Pancreatic Neoplasms - epidemiology; Pancreatic Neoplasms - pathology; Pancreatic Neoplasms - therapy; Precancerous Conditions - diagnosis; Precancerous Conditions - epidemiology; Precancerous Conditions - pathology; Prognosis; Quality of Life; Review; Risk Factors; Survival Rate; Treatment Outcome; Pancreatic adenocarcinoma; Pancreatic cancer treatment; Pancreatic cancer; Pancreatic cancer risk factors

This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further research in this understudied malignancy. Pancreatic adenocarcinoma is a lethal condition with a rising incidence, pr...