High ATF4 Expression Is Associated With Poor Prognosis, Amino Acid Metabolism, and Autophagy in Gastric Cancer

• Published in: Frontiers in oncology Vol. 11; p. 740120
• Main Authors: Wang, Mingliang, Lu, Yida, Wang, Huizhen, Wu, Youliang, Xu, Xin, Li, Yongxiang
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 17.12.2021
• Subjects: activating transcription factor 4; ATF4; autophagy; gastric cancer; metabolism; nomogram; Oncology; metabolism; autophagy; nomogram; gastric cancer; ATF4; activating transcription factor 4

The role of activating transcription factor 4 (ATF4) underlying gastric cancer (GC) remains unclear. The purpose of this study was to investigate the expression levels and biological functions of ATF4 in GC. Expression of ATF4 was detected by quantitative PCR (qPCR), Western blotting, and immunohist...