Newly Explored Faecalibacterium Diversity Is Connected to Age, Lifestyle, Geography, and Disease

• Published in: Current biology Vol. 30; no. 24; pp. 4932 - 4943.e4
• Main Authors: De Filippis, Francesca, Pasolli, Edoardo, Ercolini, Danilo
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 21.12.2020
• Subjects: biotherapeutics; Faecalibacterium prausnitzii; gut microbiome; novel probiotics; pangenome; strain diversity; novel probiotics; biotherapeutics; Faecalibacterium prausnitzii; strain diversity; pangenome; gut microbiome

Faecalibacterium is prevalent in the human gut and a promising microbe for the development of next-generation probiotics (NGPs) or biotherapeutics. Analyzing reference Faecalibacterium genomes and almost 3,000 Faecalibacterium-like metagenome-assembled genomes (MAGs) reconstructed from 7,907 human a...