Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis - Zhang, Wenting; Huang, Qinghua; Xiao, Weiwei; Zhao, Yue; Pi, Jiang; Xu, Huan; Zhao, Hongxia; Xu, Junfa; Evans, Colin E.; Jin, Hua (Frontiers in immunology, 2020)
Keywords: Adaptive Immunity - drug effects; Animals; Antibodies, Monoclonal, Humanized - therapeutic use; Antigens, Differentiation - chemistry; Antigens, Differentiation - metabolism; Antineoplastic Agents, Immunological - therapeutic use; CD47; CD47 Antigen - antagonists & inhibitors; CD47 Antigen - chemistry; CD47 Antigen - immunology; CD47 Antigen - metabolism; CD47/SIRPa axis; Humans; Immunology; immunotherapy; Immunotherapy - methods; Macrophages - immunology; Neoplasms - drug therapy; phagocytosis; Phagocytosis - drug effects; Receptors, Immunologic - chemistry; Receptors, Immunologic - metabolism; Signal Transduction - drug effects; signal-regulatory protein α (SIRPα); Xenograft Model Antitumor Assays; phagocytosis; CD47; CD47/SIRPa axis; immunotherapy; signal-regulatory protein α (SIRPα)