Activation of the Wnt Pathway by Mycobacterium tuberculosis : A Wnt-Wnt Situation

• Published in: Frontiers in immunology Vol. 8; p. 50
• Main Authors: Villaseñor, Tomás, Madrid-Paulino, Edgardo, Maldonado-Bravo, Rafael, Urbán-Aragón, Antonio, Pérez-Martínez, Leonor, Pedraza-Alva, Gustavo
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 01.02.2017
• Subjects: Immunology; microRNAs; macrophage infection; Wnt signaling; immune response; inflammation; tuberculosis

( ), an intracellular pathogenic Gram-positive bacterium, is the cause of tuberculosis (TB), a major worldwide human infectious disease. The innate immune system is the first host defense against . The recognition of this pathogen is mediated by several classes of pattern recognition receptors expre...