Activation of the Wnt Pathway by Mycobacterium tuberculosis : A Wnt-Wnt Situation

( ), an intracellular pathogenic Gram-positive bacterium, is the cause of tuberculosis (TB), a major worldwide human infectious disease. The innate immune system is the first host defense against . The recognition of this pathogen is mediated by several classes of pattern recognition receptors expre...

Full description

Saved in:
Bibliographic Details
Published inFrontiers in immunology Vol. 8; p. 50
Main Authors Villaseñor, Tomás, Madrid-Paulino, Edgardo, Maldonado-Bravo, Rafael, Urbán-Aragón, Antonio, Pérez-Martínez, Leonor, Pedraza-Alva, Gustavo
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 01.02.2017
Subjects
Immunology
microRNAs
macrophage infection
Wnt signaling
immune response
inflammation
tuberculosis
Online AccessGet full text

Cover

Abstract ( ), an intracellular pathogenic Gram-positive bacterium, is the cause of tuberculosis (TB), a major worldwide human infectious disease. The innate immune system is the first host defense against . The recognition of this pathogen is mediated by several classes of pattern recognition receptors expressed on the host innate immune cells, including Toll-like receptors, Nod-like receptors, and C-type lectin receptors like Dectin-1, the Mannose receptor, and DC-SIGN. interaction with any of these receptors activates multiple signaling pathways among which the protein kinase C, the MAPK, and the NFκB pathways have been widely studied. These pathways have been implicated in macrophage invasion, survival, and impaired immune response, thus promoting a successful infection and disease. Interestingly, the Wnt signaling pathway, classically regarded as a pathway involved in the control of cell proliferation, migration, and differentiation in embryonic development, has recently been involved in immunoregulatory mechanisms in infectious and inflammatory diseases, such as TB, sepsis, psoriasis, rheumatoid arthritis, and atherosclerosis. In this review, we present the current knowledge supporting a role for the Wnt signaling pathway during macrophage infection by and the regulation of the immune response against . Understanding the cross talk between different signaling pathways activated by will impact on the search for new therapeutic targets to fuel the rational design of drugs aimed to restore the immunological response against .
AbstractList Mycobacterium tuberculosis (M. tuberculosis), an intracellular pathogenic Gram-positive bacterium, is the cause of tuberculosis (TB), a major worldwide human infectious disease. The innate immune system is the first host defense against M. tuberculosis. The recognition of this pathogen is mediated by several classes of pattern recognition receptors expressed on the host innate immune cells, including Toll-like receptors, Nod-like receptors, and C-type lectin receptors like Dectin-1, the Mannose receptor, and DC-SIGN. M. tuberculosis interaction with any of these receptors activates multiple signaling pathways among which the protein kinase C, the MAPK, and the NFκB pathways have been widely studied. These pathways have been implicated in macrophage invasion, M. tuberculosis survival, and impaired immune response, thus promoting a successful infection and disease. Interestingly, the Wnt signaling pathway, classically regarded as a pathway involved in the control of cell proliferation, migration, and differentiation in embryonic development, has recently been involved in immunoregulatory mechanisms in infectious and inflammatory diseases, such as TB, sepsis, psoriasis, rheumatoid arthritis, and atherosclerosis. In this review, we present the current knowledge supporting a role for the Wnt signaling pathway during macrophage infection by M. tuberculosis and the regulation of the immune response against M. tuberculosis. Understanding the cross talk between different signaling pathways activated by M. tuberculosis will impact on the search for new therapeutic targets to fuel the rational design of drugs aimed to restore the immunological response against M. tuberculosis.
Mycobacterium tuberculosis ( M. tuberculosis ), an intracellular pathogenic Gram-positive bacterium, is the cause of tuberculosis (TB), a major worldwide human infectious disease. The innate immune system is the first host defense against M. tuberculosis . The recognition of this pathogen is mediated by several classes of pattern recognition receptors expressed on the host innate immune cells, including Toll-like receptors, Nod-like receptors, and C-type lectin receptors like Dectin-1, the Mannose receptor, and DC-SIGN. M. tuberculosis interaction with any of these receptors activates multiple signaling pathways among which the protein kinase C, the MAPK, and the NFκB pathways have been widely studied. These pathways have been implicated in macrophage invasion, M. tuberculosis survival, and impaired immune response, thus promoting a successful infection and disease. Interestingly, the Wnt signaling pathway, classically regarded as a pathway involved in the control of cell proliferation, migration, and differentiation in embryonic development, has recently been involved in immunoregulatory mechanisms in infectious and inflammatory diseases, such as TB, sepsis, psoriasis, rheumatoid arthritis, and atherosclerosis. In this review, we present the current knowledge supporting a role for the Wnt signaling pathway during macrophage infection by M. tuberculosis and the regulation of the immune response against M. tuberculosis . Understanding the cross talk between different signaling pathways activated by M. tuberculosis will impact on the search for new therapeutic targets to fuel the rational design of drugs aimed to restore the immunological response against M. tuberculosis .
( ), an intracellular pathogenic Gram-positive bacterium, is the cause of tuberculosis (TB), a major worldwide human infectious disease. The innate immune system is the first host defense against . The recognition of this pathogen is mediated by several classes of pattern recognition receptors expressed on the host innate immune cells, including Toll-like receptors, Nod-like receptors, and C-type lectin receptors like Dectin-1, the Mannose receptor, and DC-SIGN. interaction with any of these receptors activates multiple signaling pathways among which the protein kinase C, the MAPK, and the NFκB pathways have been widely studied. These pathways have been implicated in macrophage invasion, survival, and impaired immune response, thus promoting a successful infection and disease. Interestingly, the Wnt signaling pathway, classically regarded as a pathway involved in the control of cell proliferation, migration, and differentiation in embryonic development, has recently been involved in immunoregulatory mechanisms in infectious and inflammatory diseases, such as TB, sepsis, psoriasis, rheumatoid arthritis, and atherosclerosis. In this review, we present the current knowledge supporting a role for the Wnt signaling pathway during macrophage infection by and the regulation of the immune response against . Understanding the cross talk between different signaling pathways activated by will impact on the search for new therapeutic targets to fuel the rational design of drugs aimed to restore the immunological response against .
Author Pérez-Martínez, Leonor
Madrid-Paulino, Edgardo
Pedraza-Alva, Gustavo
Villaseñor, Tomás
Maldonado-Bravo, Rafael
Urbán-Aragón, Antonio
AuthorAffiliation 1 Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México , Cuernavaca, Morelos , Mexico
AuthorAffiliation_xml – name: 1 Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México , Cuernavaca, Morelos , Mexico
Author_xml – sequence: 1
  givenname: Tomás
  surname: Villaseñor
  fullname: Villaseñor, Tomás
  organization: Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México , Cuernavaca, Morelos , Mexico
– sequence: 2
  givenname: Edgardo
  surname: Madrid-Paulino
  fullname: Madrid-Paulino, Edgardo
  organization: Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México , Cuernavaca, Morelos , Mexico
– sequence: 3
  givenname: Rafael
  surname: Maldonado-Bravo
  fullname: Maldonado-Bravo, Rafael
  organization: Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México , Cuernavaca, Morelos , Mexico
– sequence: 4
  givenname: Antonio
  surname: Urbán-Aragón
  fullname: Urbán-Aragón, Antonio
  organization: Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México , Cuernavaca, Morelos , Mexico
– sequence: 5
  givenname: Leonor
  surname: Pérez-Martínez
  fullname: Pérez-Martínez, Leonor
  organization: Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México , Cuernavaca, Morelos , Mexico
– sequence: 6
  givenname: Gustavo
  surname: Pedraza-Alva
  fullname: Pedraza-Alva, Gustavo
  organization: Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México , Cuernavaca, Morelos , Mexico
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28203237$$D View this record in MEDLINE/PubMed
BookMark eNpVkc1LAzEQxYNUrNbePUmOXrbme3c9CKX4BYqKiseQpFkb2d3UTbbS_95uW6UehhnIe78J845Ar_a1BeAEoxGlWX5euKpqRwThdIQQ4mgPHGIhWEIJYb2duQ-GIXyuJIjllFJ-APokI4gSmh6C57GJbqGi8zX0BYwzC9_rCJ9UnH2rJdRL-LA0XisTbePaCsZW28a0pQ8uwAs47tRJ53hxsV1jjsF-ocpgh9s-AG_XV6-T2-T-8eZuMr5PDBMkJsrwIsVcTVHBmDaC5cKSzKQoN7oQ3BhupwXHNkdTkTFltNIMG4qRFpp2NQCXG-681ZWdGlvHRpVy3rhKNUvplZP_X2o3kx9-ITnJOGXZCnC2BTT-q7UhysoFY8tS1da3QeJM5ChlKMMrKdpITeNDaGzxtwYj2YUh12HILgy5DmNlOd393p_h9_T0B79bid0
CitedBy_id crossref_primary_10_3389_fimmu_2019_02390
crossref_primary_10_1155_2021_6625855
crossref_primary_10_4049_jimmunol_1900169
crossref_primary_10_3389_fimmu_2018_00679
crossref_primary_10_1016_j_tube_2018_09_007
crossref_primary_10_3389_fimmu_2019_02551
crossref_primary_10_3390_ijerph20021282
crossref_primary_10_3389_fimmu_2019_02135
crossref_primary_10_1128_spectrum_04827_22
crossref_primary_10_3389_fcimb_2021_633360
crossref_primary_10_3389_fphar_2023_1326627
crossref_primary_10_1007_s11033_021_06611_7
crossref_primary_10_1016_j_fsi_2019_09_043
crossref_primary_10_1038_s41598_020_59976_3
crossref_primary_10_1155_2017_3520581
crossref_primary_10_3389_fcell_2020_558155
crossref_primary_10_1186_s40779_020_00258_4
crossref_primary_10_1016_j_dci_2021_104111
crossref_primary_10_3389_fgene_2019_00691
crossref_primary_10_1016_j_ijmm_2022_151558
crossref_primary_10_1177_0391398818762357
crossref_primary_10_3389_fmicb_2020_01643
crossref_primary_10_1016_j_ejpb_2020_02_007
crossref_primary_10_3390_cimb43020038
crossref_primary_10_1590_1414_431x20209488
crossref_primary_10_1007_s10555_020_09878_7
crossref_primary_10_3389_fimmu_2019_02521
crossref_primary_10_1186_s13148_022_01390_9
crossref_primary_10_3389_fgene_2019_00932
crossref_primary_10_1093_infdis_jiaa785
crossref_primary_10_1016_j_jiph_2024_102486
crossref_primary_10_1016_j_mrgentox_2023_503640
crossref_primary_10_3389_fimmu_2022_1011700
crossref_primary_10_1038_s41585_018_0008_y
crossref_primary_10_1186_s12885_022_10383_z
crossref_primary_10_1096_fj_201902697RR
crossref_primary_10_1186_s13073_019_0674_2
crossref_primary_10_1111_febs_16243
Cites_doi 10.1016/j.canlet.2013.01.005
10.4049/jimmunol.1101235
10.1016/S0168-9525(00)02028-X
10.4049/jimmunol.1402498
10.1186/s12865-015-0080-5
10.1073/pnas.0605298103
10.1371/journal.ppat.0010034
10.1016/j.biocel.2016.05.015
10.1038/nri2360
10.1189/jlb.0307194
10.1016/j.meegid.2016.09.023
10.3389/fncel.2014.00175
10.1172/JCI114568
10.1073/pnas.1608255113
10.1073/pnas.1207789109
10.1016/S0092-8674(00)80754-0
10.4049/jimmunol.1201819
10.4049/jimmunol.181.10.7157
10.3389/fimmu.2013.00030
10.1007/s12015-011-9275-1
10.1038/ni.2073
10.1038/srep28530
10.1074/jbc.M406391200
10.1128/IAI.63.4.1598-1602.1995
10.1016/0092-8674(82)90409-3
10.1016/S1472-9792(13)70010-6
10.1101/gad.11.24.3286
10.1016/j.ejcb.2009.10.004
10.4049/jimmunol.169.4.2003
10.1159/000173703
10.1016/j.ejcb.2010.11.004
10.1016/j.immuni.2010.11.010
10.1084/jem.192.2.183
10.1111/j.1462-5822.2010.01544.x
10.1016/j.chom.2008.05.006
10.1038/nrd4233
10.1007/82_2012_273
10.1038/nature16937
10.1189/jlb.0905539
10.1182/blood-2002-10-3232
10.1016/j.joca.2016.11.014
10.1128/MCB.00641-14
10.1210/jc.2012-3602
10.1182/blood-2005-12-5046
10.1371/journal.pone.0053950
10.1016/S0166-2236(00)01930-5
10.1242/dev.02699
10.1186/S40880-015-0052-4
10.1139/cjm-2014-0277
10.1165/ajrcmb.15.6.8969271
10.1182/blood-2011-02-339911
10.1093/Emboj/16.13.3797
10.18632/oncotarget.12923
10.1002/j.1460-2075.1987.tb02429.x
10.1016/S1535-6108(03)00268-X
10.1093/jmcb/mjr007
10.1038/nature09783
10.1074/jbc.M110.116137
10.1002/glia.21081
10.1073/pnas.1112660108
10.1007/s10875-007-9084-0
10.1016/S0960-9822(02)00704-2
10.1073/pnas.1508426112
10.3390/ijms15035045
10.1016/j.devcel.2013.07.020
10.1155/2013/179174
10.1016/j.meegid.2015.11.031
10.1111/j.1600-0854.2012.01358.x
10.2174/1381612811306040634
10.1016/j.cell.2012.02.021
10.4049/jimmunol.169.7.3717
10.1007/s11010-015-2344-z
10.1016/S0959-437x(00)00225-2
10.1074/jbc.M512077200
10.1111/j.1574-6976.2012.00331.x
10.1101/Gad.1424006
10.1084/Jem.20062692
10.1186/s40659-016-0071-x
10.1038/357695a0
10.1125/MCB.06597-11
10.1165/ajrcmb.17.2.2469
10.1371/journal.pone.0103698
10.1371/journal.pone.0126018
10.1016/j.cell.2007.12.011
10.3389/fmicb.2011.00002
10.1371/journal.pone.0020258
10.1083/jcb.200211094
10.1096/fj.10-160994
10.1073/Pnas.022649799
ContentType Journal Article
Copyright Copyright © 2017 Villaseñor, Madrid-Paulino, Maldonado-Bravo, Urbán-Aragón, Pérez-Martínez and Pedraza-Alva. 2017 Villaseñor, Madrid-Paulino, Maldonado-Bravo, Urbán-Aragón, Pérez-Martínez and Pedraza-Alva
Copyright_xml – notice: Copyright © 2017 Villaseñor, Madrid-Paulino, Maldonado-Bravo, Urbán-Aragón, Pérez-Martínez and Pedraza-Alva. 2017 Villaseñor, Madrid-Paulino, Maldonado-Bravo, Urbán-Aragón, Pérez-Martínez and Pedraza-Alva
DBID NPM
AAYXX
CITATION
7X8
5PM
DOI 10.3389/fimmu.2017.00050
DatabaseName PubMed
CrossRef
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle PubMed
CrossRef
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic

PubMed
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1664-3224
EndPage 50
ExternalDocumentID 10_3389_fimmu_2017_00050
28203237
Genre Journal Article
Review
GroupedDBID 53G
5VS
9T4
AAFWJ
AAKDD
ACGFO
ACGFS
ACXDI
ADBBV
ADRAZ
AENEX
AFPKN
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BAWUL
BCNDV
DIK
EBS
EMOBN
GROUPED_DOAJ
GX1
HYE
IAO
IEA
IHR
IHW
IPNFZ
KQ8
M48
M~E
NPM
OK1
PGMZT
RIG
RNS
RPM
AAYXX
CITATION
7X8
ITC
5PM
ID FETCH-LOGICAL-c462t-ac5f715ad0f44bc6496e28c709cbf65cc5edf51e90d684acbab41c310b6b3b6b3
IEDL.DBID RPM
ISSN 1664-3224
IngestDate Tue Sep 17 21:00:41 EDT 2024
Fri Aug 16 04:07:03 EDT 2024
Thu Sep 26 16:09:47 EDT 2024
Sat Sep 28 08:07:48 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Keywords microRNAs
macrophage infection
Wnt signaling
immune response
inflammation
tuberculosis
Language English
License This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c462t-ac5f715ad0f44bc6496e28c709cbf65cc5edf51e90d684acbab41c310b6b3b6b3
Notes ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Edited by: Victor Manuel Baizabal-Aguirre, Universidad Michoacana de San Nicolás de Hidalgo, Mexico
Specialty section: This article was submitted to Molecular Innate Immunity, a section of the journal Frontiers in Immunology
Reviewed by: Jaya Talreja, Wayne State University School of Medicine, USA; Sahana Holla, National Cancer Institute (NIH), USA
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285348/
PMID 28203237
PQID 1869074081
PQPubID 23479
PageCount 1
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_5285348
proquest_miscellaneous_1869074081
crossref_primary_10_3389_fimmu_2017_00050
pubmed_primary_28203237
PublicationCentury 2000
PublicationDate 2017-02-01
PublicationDateYYYYMMDD 2017-02-01
PublicationDate_xml – month: 02
  year: 2017
  text: 2017-02-01
  day: 01
PublicationDecade 2010
PublicationPlace Switzerland
PublicationPlace_xml – name: Switzerland
PublicationTitle Frontiers in immunology
PublicationTitleAlternate Front Immunol
PublicationYear 2017
Publisher Frontiers Media S.A
Publisher_xml – name: Frontiers Media S.A
References 12244165 - J Immunol. 2002 Oct 1;169(7):3717-25
23012420 - Proc Natl Acad Sci U S A. 2012 Oct 9;109 (41):16600-5
17364232 - J Clin Immunol. 2007 Jul;27(4):347-62
22462580 - Traffic. 2012 Aug;13(8):1042-52
16885212 - Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12481-6
21040358 - Cell Microbiol. 2011 Mar;13(3):402-18
21502305 - J Mol Cell Biol. 2011 Jun;3(3):159-66
23420646 - Front Immunol. 2013 Feb 14;4:30
21687401 - Front Microbiol. 2011 Jan 26;2:2
20667980 - FASEB J. 2010 Nov;24(11):4599-612
17138665 - Development. 2007 Jan;134(1):3-12
21185106 - Eur J Cell Biol. 2011 Jun-Jul;90(6-7):553-9
22424234 - Cell. 2012 Mar 16;148(6):1271-83
21603945 - Stem Cell Rev. 2011 Nov;7(4):836-46
23348703 - Cancer Lett. 2013 May 1;331(2):211-9
27693402 - Infect Genet Evol. 2016 Nov;45:378-382
11672811 - Trends Neurosci. 2001 Nov;24(11):659-65
18070933 - J Exp Med. 2007 Dec 24;204(13):3077-84
20551325 - J Biol Chem. 2010 Aug 13;285(33):25221-31
17595377 - J Leukoc Biol. 2007 Sep;82(3):710-20
27210503 - Int J Biochem Cell Biol. 2016 Aug;77(Pt A):23-9
1377362 - Nature. 1992 Jun 25;357(6380):695-7
21629653 - PLoS One. 2011;6(5):e20258
21785411 - Nat Immunol. 2011 Jul 24;12(9):861-9
26895946 - Biol Res. 2016 Feb 19;49:9
11532391 - Curr Opin Genet Dev. 2001 Oct;11(5):505-12
23326547 - PLoS One. 2013;8(1):e53950
14667502 - Cancer Cell. 2003 Nov;4(5):349-60
12165526 - J Immunol. 2002 Aug 15;169(4):2003-9
10858654 - Trends Genet. 2000 Jul;16(7):279-83
24123681 - J Immunol. 2013 Nov 15;191(10):5182-95
25009466 - Front Cell Neurosci. 2014 Jun 25;8:175
20967887 - Glia. 2011 Jan;59(1):119-31
21849676 - J Immunol. 2011 Sep 15;187(6):3362-73
25246634 - Mol Cell Biol. 2014 Dec 1;34(23 ):4301-14
7534279 - Infect Immun. 1995 Apr;63(4):1598-602
27334567 - Sci Rep. 2016 Jun 23;6:28530
22067385 - Blood. 2012 Jan 12;119(2):411-21
2138634 - J Clin Invest. 1990 Apr;85(4):1304-14
23796566 - J Clin Endocrinol Metab. 2013 Aug;98(8):E1305-13
25717000 - J Immunol. 2015 Apr 1;194(7):3351-60
25084400 - PLoS One. 2014 Aug 01;9(8):e103698
16464856 - J Biol Chem. 2006 Apr 7;281(14):9507-16
25887795 - BMC Immunol. 2015 Mar 18;16:16
26643984 - Infect Genet Evol. 2016 Jan;37:259-65
24663056 - Int J Mol Sci. 2014 Mar 21;15(3):5045-62
27793042 - Oncotarget. 2016 Oct 26;:null
11805289 - Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1503-8
22473996 - Mol Cell Biol. 2012 Jun;32(12):2239-53
18981137 - J Immunol. 2008 Nov 15;181(10):7157-65
16565323 - J Leukoc Biol. 2006 Jun;79(6):1306-13
8969271 - Am J Respir Cell Mol Biol. 1996 Dec;15(6):760-70
6297757 - Cell. 1982 Nov;31(1):99-109
12771126 - J Cell Biol. 2003 May 26;161(4):769-77
18541216 - Cell Host Microbe. 2008 Jun 12;3(6):399-407
18617885 - Nat Rev Immunol. 2008 Aug;8(8):581-93
21969554 - Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17408-13
20375581 - J Innate Immun. 2009;1(3):231-43
10899905 - J Exp Med. 2000 Jul 17;192(2):183-92
26374840 - Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12163-8
16453776 - EMBO J. 1987 Jun;6(6):1765-73
11864583 - Curr Biol. 2002 Feb 19;12(4):R126-8
27914878 - Osteoarthritis Cartilage. 2016 Dec 1;:null
16601243 - Blood. 2006 Aug 1;108(3):965-73
23016862 - Curr Pharm Des. 2013;19(4):634-64
9407023 - Genes Dev. 1997 Dec 15;11(24):3286-305
18160045 - Cell. 2007 Dec 28;131(7):1378
27681624 - Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6172-E6181
12663451 - Blood. 2003 Jul 15;102(2):672-81
9271309 - Am J Respir Cell Mol Biol. 1997 Aug;17(2):209-17
23987510 - Dev Cell. 2013 Aug 26;26(4):331-45
24350246 - Biomed Res Int. 2013;2013:179174
25666090 - Mol Cell Biochem. 2015 May;403(1-2):139-47
10338208 - Cell. 1999 May 14;97(4):435-47
24981364 - Nat Rev Drug Discov. 2014 Jul;13(7):513-32
19892432 - Eur J Cell Biol. 2010 Jan;89(1):95-101
24388649 - Tuberculosis (Edinb). 2013 Dec;93 Suppl:S47-50
21248840 - Nature. 2011 Jan 20;469(7330):336-42
24965127 - Can J Microbiol. 2014 Jul;60(7):455-60
16751178 - Genes Dev. 2006 Jun 1;20(11):1394-404
21093320 - Immunity. 2010 Nov 24;33(5):713-22
26053546 - PLoS One. 2015 Jun 08;10(6):e0126018
26369691 - Chin J Cancer. 2015 Sep 14;34(12):554-62
16322770 - PLoS Pathog. 2005 Nov;1(3):279-85
23154833 - Curr Top Microbiol Immunol. 2013;374:189-209
22320122 - FEMS Microbiol Rev. 2012 May;36(3):514-32
26863187 - Nature. 2016 Feb 18;530(7590):340-3
9233789 - EMBO J. 1997 Jul 1;16(13):3797-804
15509575 - J Biol Chem. 2005 Jan 7;280(1):777-86
Blumenthal (B48) 2006; 108
Nusse (B27) 1982; 31
Codocedo (B80) 2016; 49
Schafer (B4) 2009; 1
Sasindran (B18) 2011; 2
Liang (B36) 2007; 204
Wu (B46) 2015; 16
Soldati (B14) 2012; 13
Lu (B86) 2011; 187
Shaler (B17) 2013; 4
Singh (B62) 2015; 194
Cousin (B15) 2001; 24
Murphy (B41) 2002; 169
Heisenberg (B88) 2002; 12
Le Cabec (B3) 2002; 169
Peng (B79) 2016; 8
Chaussabel (B52) 2003; 102
Schlesinger (B2) 1990; 85
Das (B71) 2013; 93
Zhao (B58) 2016; 37
Ghorpade (B70) 2012; 32
Liu (B89) 2015; 112
Small (B66) 2011; 469
Meza-Sosa (B68) 2014; 8
Bhatt (B9) 2007; 27
Zimmerli (B10) 1996; 15
Clipstone (B39) 1992; 357
D’Adamo (B74) 2016; 32
Neumann (B44) 2010; 24
Miki (B20) 2011; 7
Gengenbacher (B12) 2012; 36
Sharbati (B64) 2011; 6
Voronkov (B21) 2013; 19
Sheldahl (B38) 2003; 161
Ma (B82) 2011; 12
Pasula (B8) 1997; 17
Schaale (B19) 2011; 90
Kahn (B22) 2014; 13
Baker (B28) 1987; 6
Xu (B83) 2014; 9
Zheng (B69) 2015; 10
Brooks (B61) 2011; 13
Semenov (B33) 2007; 131
Kapinas (B81) 2010; 285
Lehtonen (B51) 2007; 82
Ferwerda (B59) 2005; 1
Fu (B84) 2014; 60
Pieters (B11) 2008; 3
Peterson (B6) 1995; 63
Liang (B35) 2003; 4
Tickenbrock (B45) 2006; 79
Farin (B26) 2016; 530
Graef (B40) 2001; 11
Ozhan (B63) 2013; 26
Duan (B24) 2016; 77
Maiti (B49) 2012; 109
Abdalla (B67) 2016; 45
Hu (B57) 2016; 6
Belver (B65) 2010; 33
Ma (B73) 2011; 3
Pan (B75) 2013; 8
Pello (B56) 2012; 119
Ferrari (B55) 1999; 97
Ehlers (B5) 2010; 89
Wu (B47) 2014; 15
Divangahi (B60) 2008; 181
Schaale (B50) 2013; 191
Rajaram (B87) 2011; 108
Cadigan (B25) 1997; 11
Staal (B29) 2008; 8
Gustafson (B42) 2006; 281
Wang (B78) 2013; 331
Kuhl (B37) 2000; 16
Sun (B77) 2015; 403
Coudreuse (B23) 2007; 134
Goldberg (B13) 2012; 148
Endo (B34) 2005; 280
Taganov (B85) 2006; 103
He (B30) 2015; 34
Aberle (B32) 1997; 16
Nau (B53) 2002; 99
Rothchild (B72) 2016; 113
Zhang (B76) 2013; 98
Jayachandran (B1) 2013; 374
Willert (B31) 2006; 20
Fratazzi (B7) 2000; 192
Halleskog (B43) 2011; 59
Trinath (B54) 2014; 34
Hossain (B16) 2013; 2013
References_xml – volume: 331
  start-page: 211
  issue: 2
  year: 2013
  ident: B78
  article-title: PRDM1 is directly targeted by miR-30a-5p and modulates the Wnt/beta-catenin pathway in a Dkk1-dependent manner during glioma growth
  publication-title: Cancer Lett
  doi: 10.1016/j.canlet.2013.01.005
  contributor:
    fullname: Wang
– volume: 187
  start-page: 3362
  issue: 6
  year: 2011
  ident: B86
  article-title: MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity
  publication-title: J Immunol
  doi: 10.4049/jimmunol.1101235
  contributor:
    fullname: Lu
– volume: 16
  start-page: 279
  issue: 7
  year: 2000
  ident: B37
  article-title: The Wnt/Ca2+ pathway – a new vertebrate Wnt signaling pathway takes shape
  publication-title: Trends Genet
  doi: 10.1016/S0168-9525(00)02028-X
  contributor:
    fullname: Kuhl
– volume: 194
  start-page: 3351
  issue: 7
  year: 2015
  ident: B62
  article-title: WNT-inflammasome signaling mediates NOD2-induced development of acute arthritis in mice
  publication-title: J Immunol
  doi: 10.4049/jimmunol.1402498
  contributor:
    fullname: Singh
– volume: 16
  start-page: 16
  year: 2015
  ident: B46
  article-title: Wnt/beta-catenin signaling reduces bacillus Calmette-Guerin-induced macrophage necrosis through a ROS-mediated PARP/AIF-dependent pathway
  publication-title: BMC Immunol
  doi: 10.1186/s12865-015-0080-5
  contributor:
    fullname: Wu
– volume: 103
  start-page: 12481
  issue: 33
  year: 2006
  ident: B85
  article-title: NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.0605298103
  contributor:
    fullname: Taganov
– volume: 1
  start-page: 279
  issue: 3
  year: 2005
  ident: B59
  article-title: NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.0010034
  contributor:
    fullname: Ferwerda
– volume: 77
  start-page: 23
  issue: Pt A
  year: 2016
  ident: B24
  article-title: The role of the wnt/beta-catenin signaling pathway in formation and maintenance of bone and teeth
  publication-title: Int J Biochem Cell Biol
  doi: 10.1016/j.biocel.2016.05.015
  contributor:
    fullname: Duan
– volume: 8
  start-page: 581
  issue: 8
  year: 2008
  ident: B29
  article-title: WNT signalling in the immune system: WNT is spreading its wings
  publication-title: Nat Rev Immunol
  doi: 10.1038/nri2360
  contributor:
    fullname: Staal
– volume: 82
  start-page: 710
  issue: 3
  year: 2007
  ident: B51
  article-title: Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells
  publication-title: J Leukoc Biol
  doi: 10.1189/jlb.0307194
  contributor:
    fullname: Lehtonen
– volume: 45
  start-page: 378
  year: 2016
  ident: B67
  article-title: MicroRNAs play big roles in modulating macrophages response toward mycobacteria infection
  publication-title: Infect Genet Evol
  doi: 10.1016/j.meegid.2016.09.023
  contributor:
    fullname: Abdalla
– volume: 8
  start-page: 175
  year: 2014
  ident: B68
  article-title: microRNAs: key triggers of neuronal cell fate
  publication-title: Front Cell Neurosci
  doi: 10.3389/fncel.2014.00175
  contributor:
    fullname: Meza-Sosa
– volume: 85
  start-page: 1304
  issue: 4
  year: 1990
  ident: B2
  article-title: Phagocytosis of leprosy bacilli is mediated by complement receptors CR1 and CR3 on human monocytes and complement component C3 in serum
  publication-title: J Clin Invest
  doi: 10.1172/JCI114568
  contributor:
    fullname: Schlesinger
– volume: 113
  start-page: E6172
  issue: 41
  year: 2016
  ident: B72
  article-title: MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1608255113
  contributor:
    fullname: Rothchild
– volume: 109
  start-page: 16600
  issue: 41
  year: 2012
  ident: B49
  article-title: The Wingless homolog Wnt5a stimulates phagocytosis but not bacterial killing
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1207789109
  contributor:
    fullname: Maiti
– volume: 97
  start-page: 435
  issue: 4
  year: 1999
  ident: B55
  article-title: A coat protein on phagosomes involved in the intracellular survival of mycobacteria
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)80754-0
  contributor:
    fullname: Ferrari
– volume: 191
  start-page: 5182
  issue: 10
  year: 2013
  ident: B50
  article-title: Wnt6 is expressed in granulomatous lesions of Mycobacterium tuberculosis-infected mice and is involved in macrophage differentiation and proliferation
  publication-title: J Immunol
  doi: 10.4049/jimmunol.1201819
  contributor:
    fullname: Schaale
– volume: 181
  start-page: 7157
  issue: 10
  year: 2008
  ident: B60
  article-title: NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity
  publication-title: J Immunol
  doi: 10.4049/jimmunol.181.10.7157
  contributor:
    fullname: Divangahi
– volume: 4
  start-page: 30
  year: 2013
  ident: B17
  article-title: Within the Enemy’s Camp: contribution of the granuloma to the dissemination, persistence and transmission of Mycobacterium tuberculosis
  publication-title: Front Immunol
  doi: 10.3389/fimmu.2013.00030
  contributor:
    fullname: Shaler
– volume: 7
  start-page: 836
  issue: 4
  year: 2011
  ident: B20
  article-title: Wnt/beta-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming
  publication-title: Stem Cell Rev
  doi: 10.1007/s12015-011-9275-1
  contributor:
    fullname: Miki
– volume: 12
  start-page: 861
  issue: 9
  year: 2011
  ident: B82
  article-title: The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma
  publication-title: Nat Immunol
  doi: 10.1038/ni.2073
  contributor:
    fullname: Ma
– volume: 6
  start-page: 28530
  year: 2016
  ident: B57
  article-title: Pathway analyses identify novel variants in the WNT signaling pathway associated with tuberculosis in Chinese population
  publication-title: Sci Rep
  doi: 10.1038/srep28530
  contributor:
    fullname: Hu
– volume: 280
  start-page: 777
  issue: 1
  year: 2005
  ident: B34
  article-title: Wnt-3a-dependent cell motility involves RhoA activation and is specifically regulated by dishevelled-2
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M406391200
  contributor:
    fullname: Endo
– volume: 63
  start-page: 1598
  issue: 4
  year: 1995
  ident: B6
  article-title: CD14 receptor-mediated uptake of nonopsonized Mycobacterium tuberculosis by human microglia
  publication-title: Infect Immun
  doi: 10.1128/IAI.63.4.1598-1602.1995
  contributor:
    fullname: Peterson
– volume: 31
  start-page: 99
  issue: 1
  year: 1982
  ident: B27
  article-title: Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
  publication-title: Cell
  doi: 10.1016/0092-8674(82)90409-3
  contributor:
    fullname: Nusse
– volume: 93
  start-page: S47
  year: 2013
  ident: B71
  article-title: Differential expression of miRNAs by macrophages infected with virulent and avirulent Mycobacterium tuberculosis
  publication-title: Tuberculosis
  doi: 10.1016/S1472-9792(13)70010-6
  contributor:
    fullname: Das
– volume: 11
  start-page: 3286
  issue: 24
  year: 1997
  ident: B25
  article-title: Wnt signaling: a common theme in animal development
  publication-title: Genes Dev
  doi: 10.1101/gad.11.24.3286
  contributor:
    fullname: Cadigan
– volume: 89
  start-page: 95
  issue: 1
  year: 2010
  ident: B5
  article-title: DC-SIGN and mannosylated surface structures of Mycobacterium tuberculosis: a deceptive liaison
  publication-title: Eur J Cell Biol
  doi: 10.1016/j.ejcb.2009.10.004
  contributor:
    fullname: Ehlers
– volume: 169
  start-page: 2003
  issue: 4
  year: 2002
  ident: B3
  article-title: Complement receptor 3 (CD11b/CD18) mediates type I and type II phagocytosis during nonopsonic and opsonic phagocytosis, respectively
  publication-title: J Immunol
  doi: 10.4049/jimmunol.169.4.2003
  contributor:
    fullname: Le Cabec
– volume: 1
  start-page: 231
  issue: 3
  year: 2009
  ident: B4
  article-title: Non-opsonic recognition of Mycobacterium tuberculosis by phagocytes
  publication-title: J Innate Immun
  doi: 10.1159/000173703
  contributor:
    fullname: Schafer
– volume: 90
  start-page: 553
  issue: 6–7
  year: 2011
  ident: B19
  article-title: Wnt signaling in macrophages: augmenting and inhibiting Mycobacteria-induced inflammatory responses
  publication-title: Eur J Cell Biol
  doi: 10.1016/j.ejcb.2010.11.004
  contributor:
    fullname: Schaale
– volume: 33
  start-page: 713
  issue: 5
  year: 2010
  ident: B65
  article-title: MicroRNAs prevent the generation of autoreactive antibodies
  publication-title: Immunity
  doi: 10.1016/j.immuni.2010.11.010
  contributor:
    fullname: Belver
– volume: 192
  start-page: 183
  issue: 2
  year: 2000
  ident: B7
  article-title: A macrophage invasion mechanism for mycobacteria implicating the extracellular domain of CD43
  publication-title: J Exp Med
  doi: 10.1084/jem.192.2.183
  contributor:
    fullname: Fratazzi
– volume: 13
  start-page: 402
  issue: 3
  year: 2011
  ident: B61
  article-title: NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages
  publication-title: Cell Microbiol
  doi: 10.1111/j.1462-5822.2010.01544.x
  contributor:
    fullname: Brooks
– volume: 3
  start-page: 399
  issue: 6
  year: 2008
  ident: B11
  article-title: Mycobacterium tuberculosis and the macrophage: maintaining a balance
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2008.05.006
  contributor:
    fullname: Pieters
– volume: 13
  start-page: 513
  issue: 7
  year: 2014
  ident: B22
  article-title: Can we safely target the WNT pathway?
  publication-title: Nat Rev Drug Discov
  doi: 10.1038/nrd4233
  contributor:
    fullname: Kahn
– volume: 374
  start-page: 189
  year: 2013
  ident: B1
  article-title: Surviving the macrophage: tools and tricks employed by Mycobacterium tuberculosis
  publication-title: Curr Top Microbiol Immunol
  doi: 10.1007/82_2012_273
  contributor:
    fullname: Jayachandran
– volume: 530
  start-page: 340
  issue: 7590
  year: 2016
  ident: B26
  article-title: Visualization of a short-range Wnt gradient in the intestinal stem-cell niche
  publication-title: Nature
  doi: 10.1038/nature16937
  contributor:
    fullname: Farin
– volume: 79
  start-page: 1306
  issue: 6
  year: 2006
  ident: B45
  article-title: Wnt signaling regulates transendothelial migration of monocytes
  publication-title: J Leukoc Biol
  doi: 10.1189/jlb.0905539
  contributor:
    fullname: Tickenbrock
– volume: 102
  start-page: 672
  issue: 2
  year: 2003
  ident: B52
  article-title: Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites
  publication-title: Blood
  doi: 10.1182/blood-2002-10-3232
  contributor:
    fullname: Chaussabel
– volume: 32
  start-page: 2239
  issue: 12
  year: 2016
  ident: B74
  article-title: Hydroxytyrosol modulates the levels of microRNA-9 and its target sirtuin-1 thereby counteracting oxidative stress-induced chondrocyte death
  publication-title: Osteoarthritis Cartilage
  doi: 10.1016/j.joca.2016.11.014
  contributor:
    fullname: D’Adamo
– volume: 34
  start-page: 4301
  issue: 23
  year: 2014
  ident: B54
  article-title: The WNT signaling pathway contributes to dectin-1-dependent inhibition of Toll-like receptor-induced inflammatory signature
  publication-title: Mol Cell Biol
  doi: 10.1128/MCB.00641-14
  contributor:
    fullname: Trinath
– volume: 98
  start-page: E1305
  issue: 8
  year: 2013
  ident: B76
  article-title: Upregulated miR-155 in papillary thyroid carcinoma promotes tumor growth by targeting APC and activating Wnt/beta-catenin signaling
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2012-3602
  contributor:
    fullname: Zhang
– volume: 108
  start-page: 965
  issue: 3
  year: 2006
  ident: B48
  article-title: The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation
  publication-title: Blood
  doi: 10.1182/blood-2005-12-5046
  contributor:
    fullname: Blumenthal
– volume: 8
  start-page: e53950
  issue: 1
  year: 2013
  ident: B75
  article-title: MiR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0053950
  contributor:
    fullname: Pan
– volume: 24
  start-page: 659
  issue: 11
  year: 2001
  ident: B15
  article-title: The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis
  publication-title: Trends Neurosci
  doi: 10.1016/S0166-2236(00)01930-5
  contributor:
    fullname: Cousin
– volume: 134
  start-page: 3
  issue: 1
  year: 2007
  ident: B23
  article-title: The making of Wnt: new insights into Wnt maturation, sorting and secretion
  publication-title: Development
  doi: 10.1242/dev.02699
  contributor:
    fullname: Coudreuse
– volume: 34
  start-page: 554
  issue: 12
  year: 2015
  ident: B30
  article-title: Wnt3a: functions and implications in cancer
  publication-title: Chin J Cancer
  doi: 10.1186/S40880-015-0052-4
  contributor:
    fullname: He
– volume: 60
  start-page: 455
  issue: 7
  year: 2014
  ident: B84
  article-title: bta-miR-29b attenuates apoptosis by directly targeting caspase-7 and NAIF1 and suppresses bovine viral diarrhea virus replication in MDBK cells
  publication-title: Can J Microbiol
  doi: 10.1139/cjm-2014-0277
  contributor:
    fullname: Fu
– volume: 15
  start-page: 760
  issue: 6
  year: 1996
  ident: B10
  article-title: Selective receptor blockade during phagocytosis does not alter the survival and growth of Mycobacterium tuberculosis in human macrophages
  publication-title: Am J Respir Cell Mol Biol
  doi: 10.1165/ajrcmb.15.6.8969271
  contributor:
    fullname: Zimmerli
– volume: 119
  start-page: 411
  issue: 2
  year: 2012
  ident: B56
  article-title: Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology
  publication-title: Blood
  doi: 10.1182/blood-2011-02-339911
  contributor:
    fullname: Pello
– volume: 16
  start-page: 3797
  issue: 13
  year: 1997
  ident: B32
  article-title: beta-catenin is a target for the ubiquitin-proteasome pathway
  publication-title: EMBO J
  doi: 10.1093/Emboj/16.13.3797
  contributor:
    fullname: Aberle
– volume: 8
  start-page: e53950
  issue: 1
  year: 2016
  ident: B79
  article-title: The crosstalk between microRNAs and the Wnt/beta-catenin signaling pathway in cancer
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.12923
  contributor:
    fullname: Peng
– volume: 6
  start-page: 1765
  issue: 6
  year: 1987
  ident: B28
  article-title: Molecular cloning of sequences from wingless, a segment polarity gene in Drosophila: the spatial distribution of a transcript in embryos
  publication-title: EMBO J
  doi: 10.1002/j.1460-2075.1987.tb02429.x
  contributor:
    fullname: Baker
– volume: 4
  start-page: 349
  issue: 5
  year: 2003
  ident: B35
  article-title: Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue
  publication-title: Cancer Cell
  doi: 10.1016/S1535-6108(03)00268-X
  contributor:
    fullname: Liang
– volume: 3
  start-page: 159
  issue: 3
  year: 2011
  ident: B73
  article-title: MicroRNAs in NF-kappaB signaling
  publication-title: J Mol Cell Biol
  doi: 10.1093/jmcb/mjr007
  contributor:
    fullname: Ma
– volume: 469
  start-page: 336
  issue: 7330
  year: 2011
  ident: B66
  article-title: Pervasive roles of microRNAs in cardiovascular biology
  publication-title: Nature
  doi: 10.1038/nature09783
  contributor:
    fullname: Small
– volume: 285
  start-page: 25221
  issue: 33
  year: 2010
  ident: B81
  article-title: miR-29 modulates Wnt signaling in human osteoblasts through a positive feedback loop
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M110.116137
  contributor:
    fullname: Kapinas
– volume: 59
  start-page: 119
  issue: 1
  year: 2011
  ident: B43
  article-title: WNT signaling in activated microglia is proinflammatory
  publication-title: Glia
  doi: 10.1002/glia.21081
  contributor:
    fullname: Halleskog
– volume: 108
  start-page: 17408
  issue: 42
  year: 2011
  ident: B87
  article-title: Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1112660108
  contributor:
    fullname: Rajaram
– volume: 27
  start-page: 347
  issue: 4
  year: 2007
  ident: B9
  article-title: Host innate immune response to Mycobacterium tuberculosis
  publication-title: J Clin Immunol
  doi: 10.1007/s10875-007-9084-0
  contributor:
    fullname: Bhatt
– volume: 12
  start-page: R126
  issue: 4
  year: 2002
  ident: B88
  article-title: Wnt signalling: a moving picture emerges from van gogh
  publication-title: Curr Biol
  doi: 10.1016/S0960-9822(02)00704-2
  contributor:
    fullname: Heisenberg
– volume: 112
  start-page: 12163
  issue: 39
  year: 2015
  ident: B89
  article-title: Endothelial microRNA-150 is an intrinsic suppressor of pathologic ocular neovascularization
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1508426112
  contributor:
    fullname: Liu
– volume: 15
  start-page: 5045
  issue: 3
  year: 2014
  ident: B47
  article-title: A caspase-dependent pathway is involved in Wnt/beta-catenin signaling promoted apoptosis in bacillus Calmette-Guerin infected RAW264.7 macrophages
  publication-title: Int J Mol Sci
  doi: 10.3390/ijms15035045
  contributor:
    fullname: Wu
– volume: 26
  start-page: 331
  issue: 4
  year: 2013
  ident: B63
  article-title: Lypd6 enhances Wnt/beta-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains
  publication-title: Dev Cell
  doi: 10.1016/j.devcel.2013.07.020
  contributor:
    fullname: Ozhan
– volume: 2013
  start-page: 179174
  year: 2013
  ident: B16
  article-title: Pattern recognition receptors and cytokines in Mycobacterium tuberculosis infection – the double-edged sword?
  publication-title: Biomed Res Int
  doi: 10.1155/2013/179174
  contributor:
    fullname: Hossain
– volume: 37
  start-page: 259
  year: 2016
  ident: B58
  article-title: SFRP1 variations influence susceptibility and immune response to Mycobacterium tuberculosis in a Chinese Han population
  publication-title: Infect Genet Evol
  doi: 10.1016/j.meegid.2015.11.031
  contributor:
    fullname: Zhao
– volume: 13
  start-page: 1042
  issue: 8
  year: 2012
  ident: B14
  article-title: Mycobacteria and the intraphagosomal environment: take it with a pinch of salt(s)!
  publication-title: Traffic
  doi: 10.1111/j.1600-0854.2012.01358.x
  contributor:
    fullname: Soldati
– volume: 19
  start-page: 634
  issue: 4
  year: 2013
  ident: B21
  article-title: Wnt/beta-catenin signaling and small molecule inhibitors
  publication-title: Curr Pharm Des
  doi: 10.2174/1381612811306040634
  contributor:
    fullname: Voronkov
– volume: 148
  start-page: 1271
  issue: 6
  year: 2012
  ident: B13
  article-title: Outwitting evolution: fighting drug-resistant TB, malaria, and HIV
  publication-title: Cell
  doi: 10.1016/j.cell.2012.02.021
  contributor:
    fullname: Goldberg
– volume: 169
  start-page: 3717
  issue: 7
  year: 2002
  ident: B41
  article-title: Endothelial cells stimulate T cell NFAT nuclear translocation in the presence of cyclosporin A: involvement of the wnt/glycogen synthase kinase-3 beta pathway
  publication-title: J Immunol
  doi: 10.4049/jimmunol.169.7.3717
  contributor:
    fullname: Murphy
– volume: 403
  start-page: 139
  issue: 1–2
  year: 2015
  ident: B77
  article-title: miR-155 promotes the growth of osteosarcoma in a HBP1-dependent mechanism
  publication-title: Mol Cell Biochem
  doi: 10.1007/s11010-015-2344-z
  contributor:
    fullname: Sun
– volume: 11
  start-page: 505
  issue: 5
  year: 2001
  ident: B40
  article-title: NFAT signaling in vertebrate development
  publication-title: Curr Opin Genet Dev
  doi: 10.1016/S0959-437x(00)00225-2
  contributor:
    fullname: Graef
– volume: 281
  start-page: 9507
  issue: 14
  year: 2006
  ident: B42
  article-title: Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M512077200
  contributor:
    fullname: Gustafson
– volume: 36
  start-page: 514
  issue: 3
  year: 2012
  ident: B12
  article-title: Mycobacterium tuberculosis: success through dormancy
  publication-title: FEMS Microbiol Rev
  doi: 10.1111/j.1574-6976.2012.00331.x
  contributor:
    fullname: Gengenbacher
– volume: 20
  start-page: 1394
  issue: 11
  year: 2006
  ident: B31
  article-title: Wnt signaling: is the party in the nucleus?
  publication-title: Genes Dev
  doi: 10.1101/Gad.1424006
  contributor:
    fullname: Willert
– volume: 204
  start-page: 3077
  issue: 13
  year: 2007
  ident: B36
  article-title: Noncanonical Wnt signaling promotes apoptosis in thymocyte development
  publication-title: J Exp Med
  doi: 10.1084/Jem.20062692
  contributor:
    fullname: Liang
– volume: 49
  start-page: 9
  year: 2016
  ident: B80
  article-title: Wnt-5a-regulated miR-101b controls COX2 expression in hippocampal neurons
  publication-title: Biol Res
  doi: 10.1186/s40659-016-0071-x
  contributor:
    fullname: Codocedo
– volume: 357
  start-page: 695
  issue: 6380
  year: 1992
  ident: B39
  article-title: Identification of calcineurin as a key signaling enzyme in lymphocyte-T activation
  publication-title: Nature
  doi: 10.1038/357695a0
  contributor:
    fullname: Clipstone
– volume: 32
  start-page: 2239
  issue: 12
  year: 2012
  ident: B70
  article-title: MicroRNA-155 is required for Mycobacterium bovis BCG-mediated apoptosis of macrophages
  publication-title: Mol Cell Biol
  doi: 10.1125/MCB.06597-11
  contributor:
    fullname: Ghorpade
– volume: 17
  start-page: 209
  issue: 2
  year: 1997
  ident: B8
  article-title: Surfactant protein A (SP-A) mediates attachment of Mycobacterium tuberculosis to murine alveolar macrophages
  publication-title: Am J Respir Cell Mol Biol
  doi: 10.1165/ajrcmb.17.2.2469
  contributor:
    fullname: Pasula
– volume: 9
  start-page: e103698
  issue: 8
  year: 2014
  ident: B83
  article-title: MicroRNA-21 (miR-21) regulates cellular proliferation, invasion, migration, and apoptosis by targeting PTEN, RECK and Bcl-2 in lung squamous carcinoma, Gejiu City, China
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0103698
  contributor:
    fullname: Xu
– volume: 10
  start-page: e0126018
  issue: 6
  year: 2015
  ident: B69
  article-title: Differential microRNA expression in human macrophages with Mycobacterium tuberculosis infection of Beijing/W and Non-Beijing/W strain types
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0126018
  contributor:
    fullname: Zheng
– volume: 131
  start-page: 1378
  issue: 7
  year: 2007
  ident: B33
  article-title: SnapShot: noncanonical Wnt signaling pathways
  publication-title: Cell
  doi: 10.1016/j.cell.2007.12.011
  contributor:
    fullname: Semenov
– volume: 2
  start-page: 2
  year: 2011
  ident: B18
  article-title: Mycobacterium tuberculosis infection and inflammation: what is beneficial for the host and for the bacterium?
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2011.00002
  contributor:
    fullname: Sasindran
– volume: 6
  start-page: e20258
  issue: 5
  year: 2011
  ident: B64
  article-title: Integrated MicroRNA-mRNA-analysis of human monocyte derived macrophages upon Mycobacterium avium subsp hominissuis infection
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0020258
  contributor:
    fullname: Sharbati
– volume: 161
  start-page: 769
  issue: 4
  year: 2003
  ident: B38
  article-title: Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos
  publication-title: J Cell Biol
  doi: 10.1083/jcb.200211094
  contributor:
    fullname: Sheldahl
– volume: 24
  start-page: 4599
  issue: 11
  year: 2010
  ident: B44
  article-title: Frizzled1 is a marker of inflammatory macrophages, and its ligand Wnt3a is involved in reprogramming Mycobacterium tuberculosis-infected macrophages
  publication-title: FASEB J
  doi: 10.1096/fj.10-160994
  contributor:
    fullname: Neumann
– volume: 99
  start-page: 1503
  issue: 3
  year: 2002
  ident: B53
  article-title: Human macrophage activation programs induced by bacterial pathogens
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/Pnas.022649799
  contributor:
    fullname: Nau
SSID ssj0000493335
Score 2.3870068
SecondaryResourceType review_article
Snippet ( ), an intracellular pathogenic Gram-positive bacterium, is the cause of tuberculosis (TB), a major worldwide human infectious disease. The innate immune...
Mycobacterium tuberculosis (M. tuberculosis), an intracellular pathogenic Gram-positive bacterium, is the cause of tuberculosis (TB), a major worldwide human...
Mycobacterium tuberculosis ( M. tuberculosis ), an intracellular pathogenic Gram-positive bacterium, is the cause of tuberculosis (TB), a major worldwide human...
SourceID pubmedcentral
proquest
crossref
pubmed
SourceType Open Access Repository
Aggregation Database
Index Database
StartPage 50
SubjectTerms Immunology
SummonAdditionalLinks – databaseName: Scholars Portal Open Access Journals
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV1NS8NAEF2kIngRv61frODFQ7RJZjeJIFLEIkJF0aK3kN3sYqVNtU3Q_Ht3Nq1arYecshnCywzzht28R8ghknY_CpkDbigdSE3NRToUTiSVTr2AJ9oKmLZv-FUHrp_Y0_fv0WMARzNHO_ST6gx7xx9v5bkp-DOcOE2_PdHdfr_AU1pWjRAH-HkPfMB8b4_J_kvFhX3fOm66nINjMhmqfcuZQVAlOER7cXRI_9my_vDQ38cpf_Sn1jJZGhNL2qwyYYXMqWyVLFRWk-UauWvKiZEZHWhqaB99zHJ6awjge1JSUdJ2KU1tW-3mok_zQqihLHqDUXdET2kTVzv4xH03r9TB10mndflwceWM7RQcCdzLnUQyHbgsSRsaQEgOEVdeKINGJIXmTEqmUs1cFTVSHkIiRSLAlYb-CS58vDZILRtkaovQQEHANUoFKg0J00K7UkkfNBPK9XhaJ0cTxOLXSjUjNtMGAh1boGMEOrZA18nBBNLYpDbuVySZGhSj2LplBWBIS51sVhB_RZt8mzoJpsD_WoCy2dN3su6zlc9mnqEoEG7_G3OHLOLrVWezd0ktHxZqz1CPXOzbjPoEmgvWiA
  priority: 102
  providerName: Scholars Portal
Title Activation of the Wnt Pathway by Mycobacterium tuberculosis : A Wnt-Wnt Situation
URI https://www.ncbi.nlm.nih.gov/pubmed/28203237
https://search.proquest.com/docview/1869074081
https://pubmed.ncbi.nlm.nih.gov/PMC5285348
Volume 8
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1da9swFL2khcFeRtt1W_oRNNhLH5zE1oftvoXQNgwyytbQvBnrWmIutVMam5K3_Yf9w_6SSnJc0vatD9aLJSOOr9C56OocgB-WtNM44h7zI_RYZtZcrCPpxah0FoQi1U7AdPpLTGbs55zPO8DbuzCuaB9l3i9vi36Z_3W1lXcFDto6scHldMwDs8mwaLAFWyGlGyn6TUN5KaW8OZI0CVg80HlR1LaKy6kVcmv-ZhKNIQ2s-fnmbvSGYr6ulNzYes534NOaM5JRM7dd6KhyDz40LpKrz_B7hK1HGVloYhgduS4rcmm43UO6InJFpis0y9bJMtcFqWqp7rG-XSzz5SkZ2c6P__7bIX_yqlH-3ofZ-dnVeOKtrRI8ZCKovBS5Dn2eZkPNmETBYqGCCMNhjFILjshVprmv4mEmIpaiTCXz0VA7KSS1zxfYLhel-gYkVCwU2soAKs1SrqX2USFlmkvlByLrwkkLWXLXKGIkJpOwSCcO6cQinTiku_C9xTQxYWvPItJSLepl4pywQmYISRe-Nhg_f639OV0IX6D_3MFKYr98YyLFSWOvI-Pg3SMP4aOdflOXfQTb1X2tjg3tqGTPpeumvZj7pp2yqOcC7wnNON6g
link.rule.ids 230,315,733,786,790,870,891,24346,27955,27956,53825,53827
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3LTtwwFL2iUyG66QNKmT6NxIZFZiaJ7STdjVDRFBiEeO-i-MZWU0gGMYmq6ar_0D_sl9SPCRroii6ysh3FOrm558on5wJsGdIeJjHzqB-jR3Mdc4mKhZegVHkQ8UxZA9PxIR-d0b1LdrkErP0Xxor2URS96rrsVcU3q628KbHf6sT6R-MdFugkQ-P-E3iq4zVgC0X6d0d6wzBk7lBSl2BJXxVl2Rgdl_UrZKb9my41BmFg2p8v5qN_SOZDreRC8tl9AeftYzvNyVWvqUUPfz5wdHz0vl7C8zkdJUM3_AqWZLUKy65B5WwNjofYtj8jE0U0WSQXVU2ONG38kc2ImJHxDPUXwTo-NyWpGyFvsbmeTIvpZzI0k__8-m2WnBS1MxV_DWe7X053Rt68C4OHlAe1lyFTkc-yfKAoFchpwmUQYzRIUCjOEJnMFfNlMsh5TDMUmaA-atYouAjNtQ6dalLJDSCRpBFXxmFQKpoxJZSPEkOqmJB-wPMubLdYpDfObCPVRYqBMLUQpgbC1ELYhc0WrFRHhDnmyCo5aaapbbIVUc11uvDGgXd3txb1LkT3YL2bYNy2749osKzr9hyct_-98hOsjE7HB-nB18P9d_DMbMXJv99Dp75t5AfNbmrx0b7LfwGfcf3Z
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3LbtQwFL2CIhAbKI-WgbYYiQ2LTCaJ7STdjdqOWmCqEVBRsYniG1sNNJlRJxEaVv0H_pAvqR-Talp2XWQVO4p1cuNz5aNzAN4b0h6lCfNokKBHC11zqUqEl6JURRjzXFkD0_ExPzyhH0_Z6UrUlxXtoyj79XnVr8szq62cVeh3OjF_Mt5jod5kaOLPCuXfhwe6ZsN4pVH_6YhvFEXMHUzqNiz1VVlVrdFyWc9CZiLgdLsxiEITgb66J_1HNG_rJVc2oNFT-NG9utOd_Oq3jejjn1uujnda2zo8WdJSMnRDnsE9WT-Hhy6ocvECvgyxi0EjU0U0aSTf64ZMNH38nS-IWJDxAvWfwTo_txVpWiEvsD2fzsv5Lhmawf8u_5opX8vGmYu_hJPRwbe9Q2-ZxuAh5WHj5chUHLC8GChKBXKachkmGA9SFIozRCYLxQKZDgqe0BxFLmiAmj0KLiJzbcBaPa3lKyCxpDFXxmlQKpozJVSAEiOqmJBByIsefOjwyGbOdCPTzYqBMbMwZgbGzMLYg3cdYJmuDHPckddy2s4zG7YVU815erDpALx-Wod8D-Ib0F4PMK7bN-9owKz79hKg13ee-RYeTfZH2eej409v4LFZiVOBb8Fac9HKbU1yGrFjP-crfcUAaA
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Activation+of+the+Wnt+Pathway+by+Mycobacterium+tuberculosis+%3A+A+Wnt-Wnt+Situation&rft.jtitle=Frontiers+in+immunology&rft.au=Villase%C3%B1or%2C+Tom%C3%A1s&rft.au=Madrid-Paulino%2C+Edgardo&rft.au=Maldonado-Bravo%2C+Rafael&rft.au=Urb%C3%A1n-Arag%C3%B3n%2C+Antonio&rft.date=2017-02-01&rft.issn=1664-3224&rft.eissn=1664-3224&rft.volume=8&rft.spage=50&rft_id=info:doi/10.3389%2Ffimmu.2017.00050&rft_id=info%3Apmid%2F28203237&rft.externalDocID=28203237
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1664-3224&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1664-3224&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1664-3224&client=summon