Temporal Changes in Cortical and Hippocampal Expression of Genes Important for Brain Glucose Metabolism Following Controlled Cortical Impact Injury in Mice

• Published in: Frontiers in endocrinology (Lausanne) Vol. 8; p. 231
• Main Authors: Zhou, June, Burns, Mark P., Huynh, Linda, Villapol, Sonia, Taub, Daniel D., Saavedra, Juan M., Blackman, Marc R.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 11.09.2017
• Subjects: angiotensin II AT1 receptor; Endocrinology; gene expression; glucose metabolism; GPR81; hexokinase; lactate; telmisartan; traumatic brain injury; angiotensin II AT1 receptor; GPR81; lactate; glucose metabolism; gene expression; hexokinase

Traumatic brain injury (TBI) causes transient increases and subsequent decreases in brain glucose utilization. The underlying molecular pathways are orchestrated processes and poorly understood. In the current study, we determined temporal changes in cortical and hippocampal expression of genes impo...