Identification of the Biomarkers and Pathological Process of Osteoarthritis: Weighted Gene Co-expression Network Analysis

• Published in: Frontiers in physiology Vol. 10; p. 275
• Main Authors: Gu, Hui-Yun, Yang, Min, Guo, Jia, Zhang, Chao, Lin, Lu-Lu, Liu, Yang, Wei, Ren-Xiong
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 19.03.2019
• Subjects: biomarkers; hub genes; osteoarthritis; pathological process; Physiology; WGCNA; pathological process; hub genes; WGCNA; biomarkers; osteoarthritis

Osteoarthritis (OA) is a joint disease resulting in high rates of disability and low quality of life. The initial site of OA (bone or cartilage) is uncertain. The aim of the current study was to explore biomarkers and pathological processes in subchondral bone samples. The gene expression profile GS...