Clinical Safety and Efficacy of Ablation for Atrial Fibrillation Patients With a History of Stroke
To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke. A total of 116 symptomatic, drug-refractory AF patients with a history of stroke, and 1:2 matched patients without a history of stroke were enrolled. Of these,...
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Published in | Frontiers in cardiovascular medicine Vol. 8; p. 630090 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
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10.03.2021
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Abstract | To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke.
A total of 116 symptomatic, drug-refractory AF patients with a history of stroke, and 1:2 matched patients without a history of stroke were enrolled. Of these, 28 cases occurred stroke within 3 months (Group 1), 88 cases with stroke history longer than 3 months (Group 2), and 232 cases without stroke (Group 3). PVI was performed in all patients, extended to ablation of linear lesions ablation. The periprocedural stroke rates and other procedure-related in-hospital complications did not differ significantly among the three groups. The maintenance rate of SR after the procedure showed no significant difference (
= 0.333), 52.7, 66.4, and 70.7% in Group 1, 2, and 3, respectively. Furthermore, the comparison between a history of stroke and those without it were also shown no significant difference (
= 0.351).
Radiofrequency ablation for AF patients occurred stroke, even within 3 months is safe and effective, without higher periprocedural complication rate and recurrence rate. |
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AbstractList | Objectives:
To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke.
Methods and Results:
A total of 116 symptomatic, drug-refractory AF patients with a history of stroke, and 1:2 matched patients without a history of stroke were enrolled. Of these, 28 cases occurred stroke within 3 months (Group 1), 88 cases with stroke history longer than 3 months (Group 2), and 232 cases without stroke (Group 3). PVI was performed in all patients, extended to ablation of linear lesions ablation. The periprocedural stroke rates and other procedure-related in-hospital complications did not differ significantly among the three groups. The maintenance rate of SR after the procedure showed no significant difference (
p
= 0.333), 52.7, 66.4, and 70.7% in Group 1, 2, and 3, respectively. Furthermore, the comparison between a history of stroke and those without it were also shown no significant difference (
p
= 0.351).
Conclusions:
Radiofrequency ablation for AF patients occurred stroke, even within 3 months is safe and effective, without higher periprocedural complication rate and recurrence rate. To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke. A total of 116 symptomatic, drug-refractory AF patients with a history of stroke, and 1:2 matched patients without a history of stroke were enrolled. Of these, 28 cases occurred stroke within 3 months (Group 1), 88 cases with stroke history longer than 3 months (Group 2), and 232 cases without stroke (Group 3). PVI was performed in all patients, extended to ablation of linear lesions ablation. The periprocedural stroke rates and other procedure-related in-hospital complications did not differ significantly among the three groups. The maintenance rate of SR after the procedure showed no significant difference ( = 0.333), 52.7, 66.4, and 70.7% in Group 1, 2, and 3, respectively. Furthermore, the comparison between a history of stroke and those without it were also shown no significant difference ( = 0.351). Radiofrequency ablation for AF patients occurred stroke, even within 3 months is safe and effective, without higher periprocedural complication rate and recurrence rate. Objectives: To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke.Methods and Results: A total of 116 symptomatic, drug-refractory AF patients with a history of stroke, and 1:2 matched patients without a history of stroke were enrolled. Of these, 28 cases occurred stroke within 3 months (Group 1), 88 cases with stroke history longer than 3 months (Group 2), and 232 cases without stroke (Group 3). PVI was performed in all patients, extended to ablation of linear lesions ablation. The periprocedural stroke rates and other procedure-related in-hospital complications did not differ significantly among the three groups. The maintenance rate of SR after the procedure showed no significant difference (p = 0.333), 52.7, 66.4, and 70.7% in Group 1, 2, and 3, respectively. Furthermore, the comparison between a history of stroke and those without it were also shown no significant difference (p = 0.351).Conclusions: Radiofrequency ablation for AF patients occurred stroke, even within 3 months is safe and effective, without higher periprocedural complication rate and recurrence rate. |
Author | Song, Zi-Liang Liu, Xu Qin, Mu Jiang, Wei-Feng Wu, Shao-Hui Zhang, Dao-Liang |
AuthorAffiliation | Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University , Shanghai , China |
AuthorAffiliation_xml | – name: Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University , Shanghai , China |
Author_xml | – sequence: 1 givenname: Zi-Liang surname: Song fullname: Song, Zi-Liang organization: Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China – sequence: 2 givenname: Shao-Hui surname: Wu fullname: Wu, Shao-Hui organization: Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China – sequence: 3 givenname: Dao-Liang surname: Zhang fullname: Zhang, Dao-Liang organization: Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China – sequence: 4 givenname: Wei-Feng surname: Jiang fullname: Jiang, Wei-Feng organization: Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China – sequence: 5 givenname: Mu surname: Qin fullname: Qin, Mu organization: Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China – sequence: 6 givenname: Xu surname: Liu fullname: Liu, Xu organization: Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China |
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Cites_doi | 10.1093/eurheartj/ehaa612 10.1111/jce.14468 10.1111/jce.13390 10.1001/archinte.165.10.1185 10.1161/CIR.0000000000000152 10.1212/WNL.0000000000003283 10.1093/ehjci/ehaa946.2431 10.1161/CIRCULATIONAHA.109.921320 10.1093/europace/eus027 10.1093/eurheartj/ehw058 10.1111/j.1540-8167.2009.01540.x 10.1111/jce.13784 10.1016/j.jjcc.2016.10.001 10.1161/STROKEAHA.115.011139 10.1016/j.ijcard.2018.12.051 10.1161/STROKEAHA.112.673558 10.1016/j.hrthm.2017.07.009 10.1016/j.jstrokecerebrovasdis.2013.05.015 10.1056/NEJMoa2019422 |
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Keywords | atrial fibrillation catheter ablation stroke safety efficacy |
Language | English |
License | Copyright © 2021 Song, Wu, Zhang, Jiang, Qin and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
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Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 This article was submitted to Cardiac Rhythmology, a section of the journal Frontiers in Cardiovascular Medicine These authors have contributed equally to this work Reviewed by: Osmar Antonio Centurion, National University of Asunción, Paraguay; Martin Ibarrola, Independent Researcher, Bella Vista, Argentina Edited by: Shimon Rosenheck, Hebrew University of Jerusalem, Israel |
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10.1161/STROKEAHA.112.673558 contributor: fullname: Ntaios – volume: 14 start-page: e445 year: 2017 ident: B18 article-title: 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: executive summary publication-title: Heart Rhythm. doi: 10.1016/j.hrthm.2017.07.009 contributor: fullname: Calkins – volume: 22 start-page: e486 year: 2013 ident: B4 article-title: Atrial fibrillation detected after acute ischemic stroke: evidence supporting the neurogenic hypothesis publication-title: J Stroke Cerebrovasc Dis. doi: 10.1016/j.jstrokecerebrovasdis.2013.05.015 contributor: fullname: González Toledo – volume: 383 start-page: 1305 year: 2020 ident: B5 article-title: Early rhythm-control therapy in patients with atrial fibrillation publication-title: N Engl J Med. doi: 10.1056/NEJMoa2019422 contributor: fullname: Kirchhof |
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Snippet | To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke.
A total of 116... Objectives: To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke. Methods... Objectives: To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke.Methods... |
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SubjectTerms | atrial fibrillation Cardiovascular Medicine catheter ablation efficacy safety stroke |
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Title | Clinical Safety and Efficacy of Ablation for Atrial Fibrillation Patients With a History of Stroke |
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