Immune Parameters and COVID-19 Infection – Associations With Clinical Severity and Disease Prognosis

• Published in: Frontiers in cellular and infection microbiology Vol. 10; p. 364
• Main Authors: Jesenak, Milos, Brndiarova, Miroslava, Urbancikova, Ingrid, Rennerova, Zuzana, Vojtkova, Jarmila, Bobcakova, Anna, Ostro, Robert, Banovcin, Peter
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 30.06.2020
• Subjects: Betacoronavirus - immunology; CD4-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - immunology; Cellular and Infection Microbiology; coronavirus 2019; Coronavirus Infections - immunology; Coronavirus Infections - pathology; COVID-19; Cytokine Release Syndrome - immunology; cytokine storm; Cytokines - immunology; eosinopenia; Eosinophils - immunology; Humans; Lung - pathology; lymphopenia; Pandemics; Pneumonia, Viral - immunology; Pneumonia, Viral - pathology; Prognosis; SARS-CoV-2; SARS-CoV2; Severity of Illness Index; COVID-19; SARS-CoV2; cytokine storm; coronavirus 2019; eosinopenia; immunoparalysis; lymphopenia

Severe acute respiratory syndrome caused by a novel 2019 coronavirus (SARS-CoV2) represents one of the most studied infectious diseases of today. The number of scientific reports and publications increases exponentially day by day. While the majority of infected subjects are asymptomatic or show mil...