CircFAM114A2 Promotes Cisplatin Sensitivity via miR-222-3p/P27 and miR-146a-5p/P21 Cascades in Urothelial Carcinoma

• Published in: Frontiers in oncology Vol. 11; p. 659166
• Main Authors: Lv, Jiancheng, Zhou, Zijian, Wang, Jingzi, Yang, Xiao, Yu, Hao, Han, Jie, Feng, Dexiang, Yuan, Baorui, Wu, Qikai, Li, Pengchao, Lu, Qiang, Yang, Haiwei
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 14.10.2021
• Subjects: chemotherapy resistance; circRNA; cisplatin; microRNA; Oncology; urothelium cancer; chemotherapy resistance; urothelium cancer; microRNA; circRNA; cisplatin

Circular RNAs (circRNAs) are non-coding RNAs that have the structure of a covalently closed loop. Increasing data have proven that circRNAs can influence the progression and chemotherapy sensitivity of tumors. Therefore, the underlying function and mechanisms of more circRNAs in progression and chem...