Sampling in Atypical Endometrial Hyperplasia: Which Method Results in the Lowest Underestimation of Endometrial Cancer? A Systematic Review and Meta-analysis

• Published in: Journal of minimally invasive gynecology Vol. 23; no. 5; p. 692
• Main Authors: Bourdel, Nicolas, Chauvet, Pauline, Tognazza, Enrica, Pereira, Bruno, Botchorishvili, Revaz, Canis, Michel
• Format: Journal Article
• Language: English
• Published: United States 01.07.2016
• Subjects: Diagnostic Errors - prevention & control; Endometrial Hyperplasia - diagnosis; Endometrial Hyperplasia - pathology; Endometrial Neoplasms - diagnosis; Endometrial Neoplasms - pathology; Endometrium - diagnostic imaging; Endometrium - pathology; Female; Humans; Hysteroscopy - methods; Precancerous Conditions - diagnosis; Precancerous Conditions - pathology; Risk Assessment; Specimen Handling - methods; Specimen Handling - statistics & numerical data; Endometrial cancer; Hysteroscopy; Endometrial sampling

Our objective was to identify the most accurate method of endometrial sampling for the diagnosis of complex atypical hyperplasia (CAH), and the related risk of underestimation of endometrial cancer. We conducted a systematic literature search in PubMed and EMBASE (January 1999-September 2013) to ide...