Are the Derived Indexes of Peripheral Whole Blood Cell Counts (NLR, PLR, LMR/MLR) Clinically Significant Prognostic Biomarkers in Multiple Myeloma? A Systematic Review And Meta-Analysis

• Published in: Frontiers in oncology Vol. 11; p. 766672
• Main Authors: Zhang, Xinwen, Duan, Jialin, Wen, Zhenyu, Xiong, Hao, Chen, Xiaomin, Liu, Yang, Liao, Kunyu, Huang, Chunlan
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 23.11.2021
• Subjects: lymphocyte-to-monocyte ratio (LMR); monocyte-to-lymphocyte ratio (MLR); multiple myeloma (MM); neutrophil-to-lymphocyte ratio (NLR); Oncology; platelet-to-lymphocyte ratio (PLR); prognosis; lymphocyte-to-monocyte ratio (LMR); platelet-to-lymphocyte ratio (PLR); meta-analysis; neutrophil-to-lymphocyte ratio (NLR); monocyte-to-lymphocyte ratio (MLR); multiple myeloma (MM); prognosis

Multiple myeloma (MM) is an incurable malignant plasma cell tumor. Whole blood cell count (WBCC) derived indexes are widely used as a predictive biomarker for various types of solid and hematological malignant tumors. Our study is to evaluate its effectiveness in MM by meta-analysis. Relevant litera...