Understanding heterogeneities in mosquito-bite exposure and infection distributions for the elimination of lymphatic filariasis

• Published in: Proceedings of the Royal Society. B, Biological sciences Vol. 285; no. 1871; p. 20172253
• Main Authors: Irvine, Michael A., Kazura, James W., Hollingsworth, T. Deirdre, Reimer, Lisa J.
• Format: Journal Article
• Language: English
• Published: England The Royal Society 31.01.2018; The Royal Society Publishing
• Edition: Royal Society (Great Britain)
• Subjects: Animals; Anopheles - physiology; Aquatic insects; Bite Heterogeneity; Biting; Decision making; Disease; Disease control; Disease transmission; Ecology; Elephantiasis, Filarial - prevention & control; Environment; Exposure; Female; Filariasis; Geospatial Model; Heterogeneity; Humans; Infections; Insect bites; Insect Bites and Stings - epidemiology; Insect Bites and Stings - etiology; Insecticide-Treated Bednets - statistics & numerical data; Lymphatic Filariasis; Male; Models, Theoretical; Mosquito Control - methods; Mosquito Vectors - physiology; Mosquitoes; Nets; Papua New Guinea - epidemiology; Parasitic diseases; Prevalence; Spatial Analysis; Spatial distribution; Spatial Heterogeneity; Vector Control; Vector-borne diseases; Papua New Guinea; lymphatic filariasis; bite heterogeneity; spatial heterogeneity; geospatial model; vector control

It is well known that individuals in the same community can be exposed to a highly variable number of mosquito bites. This heterogeneity in bite exposure has consequences for the control of vector-borne diseases because a few people may be contributing significantly to transmission. However, very fe...