Impaired sustained attention and altered reactivity to errors in an animal model of prenatal cocaine exposure

• Published in: Brain research. Developmental brain research Vol. 147; no. 1; pp. 85 - 96
• Main Authors: Gendle, Mathew H., Strawderman, Myla S., Mactutus, Charles F., Booze, Rosemarie M., Levitsky, David A., Strupp, Barbara J.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 30.12.2003
• Subjects: Animals; Attention - drug effects; Behavior, Animal - drug effects; Body Weight - drug effects; Caloric Restriction; Conditioning, Operant - drug effects; Dose-Response Relationship, Drug; Female; Intravenous injection; Pregnancy; Prenatal cocaine; Prenatal Exposure Delayed Effects; Psychomotor Performance - drug effects; Rats; Rats, Long-Evans; Reactivity to error; Rodentia; Stress, Psychological - chemically induced; Stress, Psychological - psychology; Sustained attention; Visual Perception - drug effects; Disorders of the nervous system; Sustained attention; Prenatal cocaine; Intravenous injection; Reactivity to error

Although correlations have been reported between maternal cocaine use and impaired attention in exposed children, interpretation of these findings is complicated by the many risk factors that differentiate cocaine-exposed children from SES-matched controls. For this reason, the present dose–response...