Association Between Cholinesterase Inhibitors and New-Onset Heart Failure in Patients With Alzheimer's Disease: A Nationwide Propensity Score Matching Study

• Published in: Frontiers in cardiovascular medicine Vol. 9; p. 831730
• Main Authors: Hsieh, Ming-Jer, Chen, Dong-Yi, Lee, Cheng-Hung, Wu, Chia-Ling, Chen, Ying-Jen, Huang, Yu-Tung, Chang, Shang-Hung
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 16.03.2022
• Subjects: Alzheimer's disease; Cardiovascular Medicine; cholinesterase inhibitors; new-onset heart failure; primary prevention; propensity score matching; primary prevention; propensity score matching; cholinesterase inhibitors; Alzheimer's disease; new-onset heart failure

Autonomic nervous dysfunction is a shared clinical feature in Alzheimer's disease (AD) and heart failure (HF). Cholinesterase inhibitors (ChEIs) are widely used autonomic modulators in patients with AD, but their primary preventive benefit on new-onset HF is still uncertain. This study examined...