The Mesoderm-Forming Gene brachyury Regulates Ectoderm-Endoderm Demarcation in the Coral Acropora digitifera

• Published in: Current biology Vol. 26; no. 21; pp. 2885 - 2892
• Main Authors: Yasuoka, Yuuri, Shinzato, Chuya, Satoh, Noriyuki
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 07.11.2016
• Subjects: Acropora; Animals; Anthozoa - embryology; Anthozoa - genetics; Brachyury; Cnidaria; Ectoderm - embryology; Endoderm - embryology; evo-devo; Fetal Proteins - genetics; Fetal Proteins - metabolism; gastrulation; Gene Expression Regulation, Developmental; mesoderm; pharynx formation; T-Box Domain Proteins - genetics; T-Box Domain Proteins - metabolism; transcriptome; Wnt signaling; Xenopus; evo-devo; Brachyury; Xenopus; Wnt signaling; pharynx formation; Acropora; transcriptome; Cnidaria; mesoderm; gastrulation

Blastoporal expression of the T-box transcription factor gene brachyury is conserved in most metazoans [1, 2]. Its role in mesoderm formation has been intensively studied in vertebrates [3–6]. However, its fundamental function near the blastopore is poorly understood in other phyla. Cnidarians are b...